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8 Cards in this Set

  • Front
  • Back
Classification of chronic kidney disease
0-15 - Stage 1
15-30 - Stage 2
30-60 - stage 3
60-90 - stage 4
90+ - Stage 5
Limitations of MDRD-GFR
-not for < 18 yrs
-many ethinic groups
-extremes of body habitus
-acute/unstable states (AKI)
-not validated for drug dosing
Screening for proteinuria
-proteinuria in 1 or more risk factors
-albuminuria in DM
-ACR/PCR
Top 3 causes of renal disease
-DM 31%
-glomerularnephritis 25%
-HTN 16%
Slowing progression to ESRD
-ACEI / ARBs (renoprotective beyond HTN)
-BP control
-intensive glycaemia mx
-smoking cessation
-??mx anaemia
-??statins
Mx of HTN in preservation of kidney function
proteinuria
-ACEI/ARB
-possibly CCB/Betablocker

No proteinuria
-ACEI/ARB, or CCB
who benifits most from those recieving ACEI in non diabetic CKD
those with a significant increase in serum creatinine. (< 30%). If greater check for bilateral renal artery stenosis
HTN targets in DM, agents
125/75
-ACEI/ARB
-CCB or BB or thiazide