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22 Cards in this Set
- Front
- Back
Information given to the cerebellum |
vestibular muscle stretch visual efferents copy for motor intention |
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What does the cerebellum do |
matches motor intention with sensory feedback |
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What are saccades |
quick voluntary eye movements |
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effect of cerebellar lesions on saccades |
slowed |
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Why is tone reduced in cerebellar lesions? |
gamma motor neurons that should keep intrafusal fibers harmonized aren't working |
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Recognizing basal ganglia RAM pathology |
small and fast amplitude is affected |
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why is there rigidity in RAM of patients with basal ganglia disorders |
extrapyramidal tract disinhibition |
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Essential tremor pathology (4) |
-gradual loss of purkinje cells in cerebellar hemispheres and vermis -bilateral -involves head, arms, and voice -autosomal dominant |
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essential tremor treatment |
beta blockers |
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Astrocytoma |
brain tumor that can grow into cerebellar hemisphere |
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Spinocerebellar ataxia |
-gradual loss of purkinje cells in the whole cerebellum -d/t CAG repeat expansion in different genes |
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Multiple Sclerosis |
Accumulation of lesions/ plaques in white matter |
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Hypokinetic Disorders |
parksonian disorders: -parkinson's -multiple system atrophy -rpogressive supranuclear palsy -vascular parkinson's |
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Hyperkinetic Disorders |
-huntington's -Tic disorders -hemiballism |
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What can anticholinergics be used for and why? |
-Parkinson's disease -stimulates striatum |
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parkinson' s disease cardinal features |
-resting tremor (pill rolling) -rigidity -bradykinesia -postural instability |
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Bradykinesia |
inability to start of stop movements
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Parkinson's disease treatment |
-levodopa/ dopamine agonists -anticholinergics -deep brain stimulator (subthalmic nucleus, GPi) |
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Deep brain stimulator effects what structures and how |
inhibits subthalmic nucleus and GPi |
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Huntingon's effect on neurons and symptoms |
loss of neurons in caudate nucleus causes chorea |
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Cause of hemiballism |
lesion ins subthalmic nucleus (brief high amplitude irregular movements of a limb) |
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Cerebellar disease that may be caused by prions |
Parkinson's |