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22 Cards in this Set

  • Front
  • Back

Information given to the cerebellum

vestibular


muscle stretch


visual


efferents copy for motor intention

What does the cerebellum do

matches motor intention with sensory feedback

What are saccades

quick voluntary eye movements

effect of cerebellar lesions on saccades

slowed

Why is tone reduced in cerebellar lesions?

gamma motor neurons that should keep intrafusal fibers harmonized aren't working



Recognizing basal ganglia RAM pathology

small and fast


amplitude is affected



why is there rigidity in RAM of patients with basal ganglia disorders

extrapyramidal tract disinhibition



Essential tremor pathology (4)

-gradual loss of purkinje cells in cerebellar hemispheres and vermis


-bilateral


-involves head, arms, and voice


-autosomal dominant



essential tremor treatment

beta blockers



Astrocytoma

brain tumor that can grow into cerebellar hemisphere

Spinocerebellar ataxia

-gradual loss of purkinje cells in the whole cerebellum


-d/t CAG repeat expansion in different genes

Multiple Sclerosis

Accumulation of lesions/ plaques in white matter

Hypokinetic Disorders

parksonian disorders:


-parkinson's


-multiple system atrophy


-rpogressive supranuclear palsy


-vascular parkinson's

Hyperkinetic Disorders

-huntington's


-Tic disorders


-hemiballism

What can anticholinergics be used for and why?

-Parkinson's disease


-stimulates striatum

parkinson' s disease cardinal features

-resting tremor (pill rolling)


-rigidity


-bradykinesia


-postural instability

Bradykinesia

inability to start of stop movements




Parkinson's disease treatment

-levodopa/ dopamine agonists


-anticholinergics


-deep brain stimulator (subthalmic nucleus, GPi)





Deep brain stimulator effects what structures and how

inhibits subthalmic nucleus and GPi

Huntingon's effect on neurons and symptoms

loss of neurons in caudate nucleus


causes chorea

Cause of hemiballism

lesion ins subthalmic nucleus




(brief high amplitude irregular movements of a limb)

Cerebellar disease that may be caused by prions

Parkinson's