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18 Cards in this Set
- Front
- Back
Chemotherapeutic Agents |
Used to treat disease. Agents that can selectively interfere with growth of microorgs and not the cells of the infected host. |
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Antibiotics |
Antimicrobial agents that are natural products of microorgs. |
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Synthetic Agents |
Antimicrobial compounds made in the lab but not produced by living organisms. |
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Selective toxicity |
Quality possessed by a substance that can damage or destroy a living organism in the presence of another organism that remains unaffected. |
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Antimicrobial / chemotherapeutic agent |
Capable of killing or stopping the growth of a microbe. |
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Host |
An organism that supports the growth of another organism. |
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Antibiotic resistance |
A condition whereby a microbe is unaffected by the presence of a compound used for antimicrobial activity. |
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Antimicrobial |
Capable of killing or stopping growth of a microbe. |
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Hypersensitivity |
An immune response that causes an individual to overreact to the presence of an antigen resulting in an allergic reaction. |
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Competitive Inhibitor |
A compound that competes with a substance for a position at the active site on an enzyme, but cannot be changed by the enzyme , preventing normal essential enzyme function. |
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Penicillins |
A group of closely related compounds produced by various fungi of the genus Penicillum. |
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Where have we seen the most dramatic effects of penicillin? |
Major killing diseases like pneumonia, scarlet fever, staphloccal disease, gonorrhea, syphilis |
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Why did the effectiveness diminish? |
Great overuse in the 1950s |
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Why did it become effective again? |
It was discovered that chemical chains could be added synthetically to attack certain microbes. |
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Where is Penicillin G unstable? |
In the stomach, cannot be taken orally. |
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Where is Penicillin V stable? |
In acid, can be absorbed from the intestinal tract, |
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Why is Penicillin a treatment of choice? |
Its non-toxicity to host and cost-effectiveness. |
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What is used to treat penicillin-resistant staph infection? |
Semisynthetic penicillins |