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18 Cards in this Set

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  • Back

Chemotherapeutic Agents

Used to treat disease. Agents that can selectively interfere with growth of microorgs and not the cells of the infected host.

Antibiotics

Antimicrobial agents that are natural products of microorgs.

Synthetic Agents

Antimicrobial compounds made in the lab but not produced by living organisms.

Selective toxicity

Quality possessed by a substance that can damage or destroy a living organism in the presence of another organism that remains unaffected.

Antimicrobial / chemotherapeutic agent

Capable of killing or stopping the growth of a microbe.

Host

An organism that supports the growth of another organism.

Antibiotic resistance

A condition whereby a microbe is unaffected by the presence of a compound used for antimicrobial activity.

Antimicrobial

Capable of killing or stopping growth of a microbe.

Hypersensitivity

An immune response that causes an individual to overreact to the presence of an antigen resulting in an allergic reaction.

Competitive Inhibitor

A compound that competes with a substance for a position at the active site on an enzyme, but cannot be changed by the enzyme , preventing normal essential enzyme function.

Penicillins

A group of closely related compounds produced by various fungi of the genus Penicillum.

Where have we seen the most dramatic effects of penicillin?

Major killing diseases like pneumonia, scarlet fever, staphloccal disease, gonorrhea, syphilis

Why did the effectiveness diminish?

Great overuse in the 1950s

Why did it become effective again?

It was discovered that chemical chains could be added synthetically to attack certain microbes.

Where is Penicillin G unstable?

In the stomach, cannot be taken orally.

Where is Penicillin V stable?

In acid, can be absorbed from the intestinal tract,

Why is Penicillin a treatment of choice?

Its non-toxicity to host and cost-effectiveness.

What is used to treat penicillin-resistant staph infection?

Semisynthetic penicillins