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16 Cards in this Set
- Front
- Back
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Single stranded RNA(+) strand viruses
genome serves as mRNA |
rhinovirus (cold)
enterovirus (polio) togavirus (rubella/german measles) |
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Single stranded RNA (-) strand
viruses Genome is the template from which mRNA is transcribed |
Orthomyxovirus (influenza)
rhabdovirus (rabies) morbillivirus (measles) paramyxovirus (mumps) RSV (bronchiolitis & pneumonia) |
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Double stranded RNA (+/-) strands
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Reovirus (resp and GI sxs)
Coronavirus (SARS) |
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Retroviruses
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HIV
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Single stranded DNA viruses
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Parvovirus (gastroenteritis, canine distemper)
Bacteriophage (vectors,biotech) |
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Double stranded DNA viruses
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HSV1
HSV2 Herpes zoster CMV Papovavirus (genitral warts, plantar warts Poxvirus (small pox) |
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Stages of the viral life cycle
A. DNA viruses Step1 |
Attachment (virion-virulent viral particle)
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step2
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penetration (pinocytotic mechanism)
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step3
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uncoating (ion transport channels) and transfer of viral DNA to nucleus
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step4
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early transcription into viral mRNA
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step5
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early translation of viral mRNA into enzymes for viral DNA synthesis
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step6
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synthesis of viral DNA and late transcription of viral mRNA
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step7
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late translation of mRNA into viral structural protiens (interferons alpah, beta, gamma)
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step8
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assembly of virus particles in nucleus (genome encased by new capsid proteins)
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step9
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budding atom nucleus and release of virions (also by lysis)
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Retrovirus stages
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binding-> uncoating -> reverse transcriptase + RNASE (genomic RNA -> double stranded DNA) ->integration into cell nucleus->transcription to proviral RNA ->viral mRNA undergoes translation to form viral proteins or genomic RNA assembles into cell membrane -> release required by HIV protease
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