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285 Cards in this Set
- Front
- Back
- 3rd side (hint)
morphine
|
reduce intracellular Ca, increase K+
|
|
|
Codeine
|
reduce intracellular Ca, increase K+
|
|
|
hydromorphone
|
reduce intracellular Ca, increase K+
|
|
|
oxymorphone
|
reduce intracellular Ca, increase K+
|
|
|
levorphanol
|
reduce intracellular Ca, increase K+
|
|
|
dextromethorphan
|
reduce intracellular Ca, increase K+
|
|
|
hydrocodone
|
reduce intracellular Ca, increase K+
|
|
|
oxycodone
|
reduce intracellular Ca, increase K+
|
|
|
meperidine
|
reduce intracellular Ca, increase K+
|
|
|
tramadol
|
reduce intracellular Ca, increase K+
|
|
|
metahdone
|
reduce intracellular Ca, increase K+
|
|
|
fentanyl
|
reduce intracellular Ca, increase K+
|
|
|
sufentanil
|
reduce intracellular Ca, increase K+
|
|
|
alfentanil
|
reduce intracellular Ca, increase K+
|
|
|
Remifentanil
|
reduce intracellular Ca, increase K+
|
|
|
Bupronorphine
|
reduce intracellular Ca, increase K+ and inhibits u receptor
|
|
|
Butorphanol
|
reduce intracellular Ca, increase K+ and inhibitus u receptor
|
|
|
nalbuphine
|
inhibits u receptor
|
|
|
naloxone
|
inhibits u receptor
|
|
|
diphenoxylate
|
inhibits ach realse of intestinal cholinergic neurons
|
|
|
loperamide
|
inhibit ach rease of intestinal cholinergic neuron
|
|
|
colchicine
|
increase synovial ph
|
|
|
allopurinol
|
xanthine oxidasae inhibitor
|
|
|
oxypurinol
|
xanthine oxidase inhibitor
|
|
|
febuxostat
|
xanthine oxidase inhibitor
|
|
|
probenecid
|
URAT 1 inhbitor
|
|
|
sulfinpyrazone
|
URAT 1 inhibitor
|
|
|
rasburicase
|
convert URATE to allantion
|
|
|
pegloticase
|
convert URATE to allantion
|
|
|
auranofin
|
lysosomal inhibition in macrophage
|
|
|
methotrexate
|
block T cell proliferation
|
|
|
leflunamide
|
block T cell proliferation
|
|
|
sulfasalazine
|
unclear
|
|
|
warfarin
|
vitamin K antagonist
|
|
|
heparin
|
inhibit thrombin and factor Xa
|
|
|
daltperin
|
inhibit thrombin and factor Xa
|
|
|
enoxaparin
|
inhibit thrombin and factor Xa
|
|
|
fondaparinux
|
inhibit Xa
|
|
|
hirudin
|
Irreversible inhibition of thrombin
|
|
|
lepirudin
|
irreversible inhibition of thrombin
|
|
|
desirudin
|
irreversible inhibition of thrombin
|
|
|
bivalrudin
|
reversible inhibition of thrombin
|
|
|
argatroban
|
reversible inhibition of thrombin
|
|
|
dabigatran
|
reversible inhibition of thrombin
|
|
|
acetylsalicylic acid
|
irreversible inhibition of COX1
|
|
|
triflusal
|
irreversible inhibition of COX1
|
|
|
sulfinpyrazole
|
reversible inhibition of cox-1
|
|
|
dipyradimole
|
pde3 inhibitor
|
|
|
cilostazol
|
pde3 inhibitor
|
|
|
ticlopidine
|
p2y receptor antagonist
|
|
|
clopidogrel
|
p2y12 inhibitor
|
|
|
prasugrel
|
P2Y 12 inhibitor
|
|
|
abciximab
|
Glycoportein IIb/IIIa
|
|
|
eptifibatide
|
glycoprotein IIb/IIIa
|
|
|
tirofiban
|
glycoprotein IIb/IIIa receptor antagonist
|
|
|
papaverine
|
pde 3 inhibitor
|
|
|
quinidine
|
na channel blocker
|
|
|
procainamide
|
na channel blocker
|
|
|
disopyramide
|
na channel blocker
|
|
|
lidocaine
|
na channel blocker
|
|
|
clopidogrel
|
p2y12 inhibitor
|
|
|
prasugrel
|
P2Y 12 inhibitor
|
|
|
abciximab
|
Glycoportein IIb/IIIa
|
|
|
eptifibatide
|
glycoprotein IIb/IIIa
|
|
|
tirofiban
|
glycoprotein IIb/IIIa receptor antagonist
|
|
|
papaverine
|
pde 3 inhibitor
|
|
|
quinidine
|
na channel blocker
|
|
|
procainamide
|
na channel blocker
|
|
|
disopyramide
|
na channel blocker
|
|
|
lidocaine
|
na channel blocker
|
|
|
tocainide
|
na channel blocker
|
|
|
mexiletine
|
na channel blocker
|
|
|
phenytion
|
na channel blocker
|
|
|
flecainide
|
na channel blocker
|
|
|
encainde
|
na channel blocker
|
|
|
propaferone
|
na channel blocker
|
|
|
moricizine
|
na channel blocker
|
|
|
propanolol
|
non selectinve beta blocker
|
|
|
sotalol
|
non selective beta blocker
|
|
|
bretylium
|
inhibit repolarization/K+ channel blocker
|
|
|
amiodarone
|
alters ion permeability
|
|
|
dronedarone
|
alters ion permeability
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
amiodarone
|
alters ion permeability
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
verapamil
|
Ca channel blocker
|
|
|
dronedarone
|
alters ion permeability
|
|
|
amiodarone
|
alters ion permeability
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
dronedarone
|
alters ion permeability
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
adenosine
|
slows AV node conduction
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
amiodarone
|
alters ion permeability
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
dronedarone
|
alters ion permeability
|
|
|
verapamil
|
Ca channel blocker
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
verapamil
|
Ca channel blocker
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
adenosine
|
slows AV node conduction
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
verapamil
|
Ca channel blocker
|
|
|
adenosine
|
slows AV node conduction
|
|
|
amiodarone
|
alters ion permeability
|
|
|
amiodarone
|
alters ion permeability
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
amiodarone
|
alters ion permeability
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
dronedarone
|
alters ion permeability
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
dronedarone
|
alters ion permeability
|
|
|
dronedarone
|
alters ion permeability
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
adenosine
|
slows AV node conduction
|
|
|
ibutilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
dofetilide
|
inhibit repolarization/ K+ channel blocker
|
|
|
verapamil
|
Ca channel blocker
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
verapamil
|
Ca channel blocker
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
verapamil
|
Ca channel blocker
|
|
|
diltiazem
|
Ca channel blocker
|
|
|
adenosine
|
slows AV node conduction
|
|
|
adenosine
|
slows AV node conduction
|
|
|
adenosine
|
slows AV node conduction
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
phenobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
pentobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
amobarbital
|
GABaa receptor agonist by barbituate receptor agonist
|
|
|
glutethimide
|
unknown
|
|
|
ethchlorvynol
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
glutethimide
|
unknown
|
|
|
chloral hydrate
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
ethchlorvynol
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
paraldehyde
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
chloral hydrate
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
glutethimide
|
unknown
|
|
|
paraldehyde
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
ethchlorvynol
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
zolpidem
|
GABA agonist/BZD omega-1 receptor agonist
|
|
|
zolpidem
|
GABA agonist/BZD omega-1 receptor agonist
|
|
|
chloral hydrate
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
Zaleplon
|
BZD omega-1 receptor agonist
|
|
|
Zaleplon
|
BZD omega-1 receptor agonist
|
|
|
Eszopiclone
|
BZD omega-1/omega-2 receptor agonist
|
|
|
paraldehyde
|
enhance gaba receptor/inhibits NMDA receptors
|
|
|
Eszopiclone
|
BZD omega-1/omega-2 receptor agonist
|
|
|
Ramelteon
|
melatonin receptor agonist
|
|
|
zolpidem
|
GABA agonist/BZD omega-1 receptor agonist
|
|
|
Ramelteon
|
melatonin receptor agonist
|
|
|
Zaleplon
|
BZD omega-1 receptor agonist
|
|
|
phenytion
|
Na channel blocker
|
|
|
Eszopiclone
|
BZD omega-1/omega-2 receptor agonist
|
|
|
phenytion
|
Na channel blocker
|
|
|
mephenytoin
|
na channel blocker
|
|
|
mephenytoin
|
na channel blocker
|
|
|
Ramelteon
|
melatonin receptor agonist
|
|
|
phenytion
|
Na channel blocker
|
|
|
mephenytoin
|
na channel blocker
|
|
|
fosphenoytion
|
prodrug of phenytion
|
|
|
ethotion
|
na channel blocker
|
|
|
ethosuccinimide
|
na channel blocker
|
|
|
mephsuccinimide
|
na channel blocker
|
|
|
phensuccinimide
|
na channel blocker
|
|
|
primidone
|
prodrug of phenobarbital
|
|
|
valproic acid
|
inhibitor of succinimc semiladehyde dehydrogenase
|
|
|
sodium valproate
|
inhibitor of succinic semialdehyde dehydrogenase
|
|
|
divalproex
|
inhibitor of succinic semialdehyde dehydrogenase
|
|
|
gabapentin
|
L amino acid protein transporter agonist
|
|
|
pregablin
|
inhibit release of NE glutemate and substance P
|
|
|
carbamazepine
|
na channel blocker
|
|
|
oxcarbazepine
|
na channel blocker
|
|
|
lamotrigine
|
na channel blocker
|
|
|
ferbamate
|
NMDA receptor antagonist/Na Ca receptor blocker
|
|
|
tiagibine
|
gaba reuptake inhibitor
|
|
|
topiramate
|
na and ca channel blocker
|
|
|
levetiracetam
|
upregulate gaba synaptic transmission
|
|
|
zonisamide
|
na and ca channel blocker
|
|
|
aprepitant
|
substance P/NK antagonist
|
|
|
chlordiazepoxide
|
gaba agonist by benzodiazepine omega receptor agonist
|
|
|
flumazeinil
|
gaba antagonist by BZD omega receptor antagonist
|
|
|
buspirone
|
5-HT autoreceptor agonist/functional antagonist 5-ht postsynaptic receptors.
|
|
|
phenelzine
|
MAOI
|
|
|
isocarboxazid
|
MAOI
|
|
|
tranylcypromine
|
MAOI
|
|
|
imipramine
|
inhibit 5-ht and ne reuptake
|
|
|
desipramine
|
inhibit 5-ht and ne reuptake
|
|
|
trimipramine
|
inhibit 5-ht and ne reuptake
|
|
|
clomipramine
|
inhibit 5-ht and ne reuptake
|
|
|
doxepin
|
inhibit 5ht and ne reuptake
|
|
|
amoxapine
|
inhibit 5ht and ne reuptake and dopamine receptor antagonist
|
|
|
bupropion
|
inhibit dopamine and ne reuptake
|
|
|
venlafaxine
|
inhibit 5ht and ne reuptake
|
|
|
trazodone
|
inhibit 5ht reuptake and 5ht receptor antagonist
|
|
|
nafazodone
|
inhibit 5ht reuptake and 5ht receptor antagonist
|
|
|
maprotonine
|
inhibit 5ht and ne reuptake
|
|
|
mirtazapine
|
inhibit 5ht and ne reuptake
|
f
|
|
fluvoxamine
|
SSRI
|
|
|
fluoxetine
|
SSRI
|
|
|
setraline
|
SSRI
|
|
|
paroxetine
|
SSRI
|
|
|
citalopram
|
SSRI
|
|
|
escitalopram
|
SSRI
|
|
|
Duloxetine
|
inhibit NE and 5HT reuptake
|
|
|
celecoxib
|
rev. selective inhibition of COX-2
|
|
|
streptokinase
|
plasminogen activator
|
|
|
urokinase
|
plasminogen activator
|
|
|
reteplase
|
plasminogen activator
|
|
|
tenecteplase
|
plasminogen activator
|
|
|
etodolac
|
rev. inhibition of cox1 and cox2
|
|
|
oxaprozin
|
rev. inhibition of cox 1 and cox2
|
|
|
mefenamic acid
|
rev. inhibition of cox 1 and cox2
|
|
|
meclofenamate
|
rev. inhibition of cox 1 and cox2
|
|
|
piroxicam
|
rev. inhibition of cox 1 and cox2
|
|
|
meloxicam
|
rev. inhibition of cox 1 and cox2
|
|
|
nabumetone
|
rev. inhibition of cox 1 and cox2
|
|
|
ketorolac
|
rev. inhibition of cox 1 and cox2
|
|
|
tomentin
|
rev. inhibition of cox 1 and cox2
|
|
|
silindac
|
rev. inhibition of cox 1 and cox2
|
|
|
diflunisal
|
rev. inhibition of cox 1 and cox2
|
|
|
salicylamide
|
rev. inhibition of cox 1 and cox2
|
|
|
acetylsalicylic acid
|
irrev. inhibition of cox 1 and cox2
|
|
|
cromolyn sodium
|
inhibits H1 release
|
|
|
nedocromil sodium
|
inhibits H1 release
|
|
|
lodaxamide
|
mast cell stabilizer
|
|
|
pemirolast
|
inhibits H1 release
|
|
|
methapyrilene
|
H1 receptor blocker
|
|
|
antazoline
|
H1 receptor blocker
|
|
|
diphenhydramine
|
H1 receptor blocker
|
|
|
carbinoxamine
|
H1 receptor blocker
|
|
|
doxylamine
|
H1 receptor blocker
|
|
|
setastine
|
H1 receptor blocker
|
|
|
clemastine
|
H1 receptor blocker
|
|
|
pheniramine
|
H1 receptor blocker
|
|
|
chlorpheniramie
|
H1 receptor blocker
|
|
|
brompheniramine
|
H1 receptor blocker
|
|
|
dexchlorpheniramine
|
H1 receptor blocker
|
|
|
dexbropheniarmine
|
H1 receptor blocker
|
|
|
pyrrobutamine
|
H1 receptor blocker
|
|
|
triprolidine
|
H1 receptor blocker
|
|
|
dimethindene
|
H1 receptor blocker
|
|
|
phenindamine
|
H1 receptor blocker
|
|
|
promethazine
|
H1 receptor blocker
|
|
|
trimeprazine
|
H1 receptor blocker
|
|
|
methdilazine
|
H1 receptor blocker
|
|
|
cyproheptadine
|
H1 receptor blocker
|
|
|
azatadine
|
H1 receptor blocker
|
|
|
cyclizine
|
H1 receptor blocker
|
|
|
chlorcyclizine
|
H1 receptor blocker
|
|
|
meclizine
|
H1 receptor blocker
|
|
|
buclizine
|
H1 receptor blocker
|
|
|
oxatomide
|
H1 receptor blocker
|
|
|
hydroxyzine
|
H1 receptor blocker
|
|
|
terfenadine
|
H1 receptor blocker
|
|
|
fexofenadine
|
H1 receptor blocker
|
|
|
cetirizine
|
H1 receptor blocker
|
|
|
levocetirizine
|
H1 receptor blocker
|
|
|
loratidine
|
H1 receptor blocker
|
|
|
desloratidine
|
H1 receptor blocker
|
|
|
cimetidine
|
H2 receptor blocker
|
|
|
ranitidine
|
H1 receptor blocker
|
|
|
lansoprazole
|
ppi
|
|
|
rabeprazole
|
ppi
|
|
|
pantoprazole
|
ppi
|
|