Med Admin: Ircc Test 2 Lipid Lowering Drugs

Front 1

A drug that reduces lipid levels

Back 1

antilipemic

Front 2

a fat-soluble crystalline steroid alcohol found in animal fats and oils and egg yolk and widely distributed in the body, especially in the bile, blood, brain tissue, liver, kidneys, adrenal glands, and myyelin sheaths of nerve fibers

Back 2

Cholesterol

Front 3

Elevation of lipids in the blood stream

Back 3

hyperlipidemia

Front 4

HMG-CoA Redutase Inhibitors (statins)

Back 4

decrease cholesterol by blocking liver production of cholesterol

Front 5

Statin side effects

Back 5

GI symptoms
Rare but SERIOUS hepatoxicity (liver toxicity) and rhabdomyolysis (the break down of muscle fibers resulting in the release of muscle fiber contents into the blood stream)

Front 6

Most of these are metabilized by P-450 enzymes

Back 6

Statins

Front 7

Contraindicated in pregnant and nursing women

Back 7

Statins

Front 8

Take in the evening

Back 8

Statins

Front 9

Decreases LDL by binding to cholesterol-containing bile acids in the intestines than eliminating them

Back 9

Bile Acid Sequestrants

Front 10

name two bile acid sequestrants

Back 10

cholestyramine (Questran)
colestipol (Colestid)

Front 11

at what time should Questran or Colestid be taken?

Back 11

since this is a bile acid sequestrant it should be taken one hour ac (antes de comer, before eating)

Front 12

side effects of bile acid sequestrants

Back 12

constipation, bloating, indegistion, N/V, fecal impaction

Front 13

Vitamin B3 aka.

Back 13

Niacin

Front 14

Action of Niacin

Back 14

It decreases total cholesterol, LDL and triglycerides
Increases HDL

Front 15

Niacin may be used alone or incombination with this other drug (suffix)?

Back 15

Statins

Front 16

Fibric Acid Derivatives aka

Back 16

Fibrates

Front 17

Best used in lowering triglycerides

Back 17

Fibrates

Front 18

Name two fibrate drugs

Back 18

fenobrate (Tricor)
gemfibrozil (Lopid)

Front 19

This drug is not used with statins

Back 19

Fibric Acid Derivatives (Fibrates)

Front 20

side effect of Fibrates

Back 20

GI symptoms

Front 21

Action of the new classification Azetidinones

Back 21

Helps block intestinal absorption of cholesterol that comes from food

Front 22

Name one drug in the Azetidinones classification

Back 22

ezetimibe (Zetia)
{like a-zeti-dinones}

Front 23

Side effects of azetidinones

Back 23

dizziness, joint pains, tiredness

Front 24

what food substance has lipid lowering effects

Back 24

Garlic

Front 25

what is the known action of garlic

Back 25

it inactivates enzymes involved in lipid synthesis

Front 26

How do we know when the antilipemics have been effective

Back 26

when the LDL has decreased

Front 27

Nursing implications for antilipemics

Back 27

1.monitor for effectiveness
2.teach non-drug interventions
3.do not d/c the drug
4.monitor liver function
5.watch for rhabdomyolysis
6.never give a powder form of antilipemics plain

Front 28

What theraputic levels for LDL's do we want for:
high risk-labs
low risk-labs

Back 28

<100 (high risk pt should be under 100)
<160 (low risk pt can be under 160)

Front 29

What are the non-drug interventions that should be taught to you patient experiencing hyperlipidemia

Back 29

changing diet/diatery modifications, exercise as in do some regular exercise (the FDA's new food pyramid says 30 minutes of moderate exercise 5 days a week)

Front 30

Contraindications in antilipemics

Back 30

hypersensitivity reatctions
biliary obstruction
liver disease