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5 Cards in this Set

  • Front
  • Back
Enymatic drug inactivation
1) All Beta-lactams (lactamases).
2) Aminoglycosides (acetylation).
3) Chloramphenicol (acetylation).
4) Streptogramins (lactonases).
Mutated drug receptor
1) Fluoroquinolones.
2) Metronidazole.
3) Sulfonamides & Trimethoprim.
4) Penicillins (e.g. MRSA).
5) Aminoglycosides.
6) Streptogramins.
7) Linezolid.
Decreased Membrane Permeability to Drug
1) Penicillins (porins).
2) Tetracyclines (efflux pump). (Tigecycline less sensitive.)
3) Macrolides (efflux pump). (Ketolides less sensitive.)
Ribosomal Methylation
1) Clindamycin
2) Macrolides (ketolides less sensitive)
3) Streptogramins
Expression of Ribosomal Protection Proteins
1) Tetracyclines (tigecycline less sensitive).