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14 Cards in this Set

  • Front
  • Back

Misoprostol

(Cytotec)

PEG agonist


increases mucus and bicarbonate production


decreases gastric acid


Used in combo w/ mifepristone for aborttion



Mifepristone

(Korlyn)

Progesterone receptor antagonist


Dinoprostone

(Cervidil)

Induction of labor or abortion

Latanoprost

Xalatan


PG agalog


glaucoma and ocular HT

Bimatoprost

(Lumigan)


Treatment of hypotrichosis of eye lashes


Pregnancy category C

Indomethacin

Indocin


PG synthesis inhibitor


Closure of ductus arteriosis

Epoprostanol

Flolan


PGI2


Dilate ductus


Inhibits platelet aggregation

Bosenten

Tracleer


Vasodilation


Endothelin competitive receptor antag (IV)


*Embryo Fetal Toxicity*


Iloprost

Ventavis


PGI2


Endothelin competitive receptor antag (Inhalation)


Treatment of NYHA Class III or IV

Treprostinil

Ramodulen


Prostacyclin analog


Endothelin competitive receptor antag (SC)


No refrigeration needed

Sildenafil

Revatio


Inhibit PDE-5


Vasodilating effects increase endogenous NO

Tadalafil

Adcirca


Inhibit PDE-5Vasodilating effects increase endogenous NO

Selexipag

Uptravi


Oral IP prostacyclin receptor agonist for PAH


AR: HA, diarrhea, flushing

Riociguat

Adempas


1) stabilize binding of NO to guanylate cyclase


2) directly stimulates guanylate cyclase


Increase cGMP causing vasolation


*Embryo fetal toxicity