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15 Cards in this Set
- Front
- Back
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Hyperuricemia
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uric acid >6-7mg/dl
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Colchicine
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traditional treatment used since middle ages. Reduces neutrophil emmigration, blocls chemical junk
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Purines
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breakdown causes production of uric acid
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solubility of uric acid
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6.5 mg/dl at 37 C
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majority of gout patients
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men near the age of 40
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factors increasing hyperuricemia risk
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alcohol, obesity, renal dysfunction
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cause of hyperuricemia
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underexcretion (90%)
Overproduction |
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acute attack of gout
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usually attack 1 joint
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urate crystals in soft tissue
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gouty tophi
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monosodium urate crystals
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negatively birefringent
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Benecid (probencid)
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uricosuric drug to increase uric acid secretion
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Zylloprim (allopurinol)
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inhibits xanthine oxidase
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calcium pyrophosphate crystals
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found in pseudogout
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positively birefringent
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calcium pyrophosphate crystals
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APAP
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tylenol
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