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27 Cards in this Set
- Front
- Back
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where are ryanodine receptors
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external surface of sarcoplasmic reticulum
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where are L type receptors
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plasma membrane t tubules
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what 2 mechanisms increase cytosolic Ca
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L type from plasma membrane directly
Ryanodine receptors on sarcoplasmic reticulum |
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what causes myosin to detach from actin
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ATP binding
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what energizes the cross bridge
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hydrolysis of ATP
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blood moved per unit of time
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CO
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first heart sound
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AV valve
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second heart sound
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aortic and pulmonary valves closing
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stenotic valve
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narrowed
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insufficient valve
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leaky
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Flow
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delta P/R
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R
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8Ln/pi r^4
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systole
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ventricles contracting
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Preload
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amount of blood in the heart before contraction ...... end diastolic volume
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afterload
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pressure against which the ventricles pump
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fill heart with more blood
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actin and myosin line up more optimal
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sympathetic regulation
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heart will relax more quickly after contraction
and stronger more rapid contraction |
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sympathetic receptor
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Beta adrenergice
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mechanisme of symp
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epi or nor epi
beta adrenergic adenylate cyclase camp |
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what 4 things does active cAMP affect
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DHP
ryanodine thin filiment activation cross bridge cycling |
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SA controls
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heart rate
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AV controls
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conduction
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muscles control
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contractility
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increase SV
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epi
norepi end diastolic volume |
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increase heart rate
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epi
norepi |
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ejection fraction
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edv-esv/edv
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hypertrophic cardiomyopathy
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preload dependant
intraventricular septum .... affects ejection |
