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18 Cards in this Set

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How can measuring the incidence of a disease help us?
1. decide whether an epidemic is in progress 2. monitor effect of prevention programmes 3. identify potential hazard danger.
What type of diseases is incidence important for?
'Diseases' of very short duration e.g. stroke. The focus is on events.
What does the incidence of a disease not give us information about?
the burden of disease. also important to know about the number of existing cases to know extent of need for particular health services.
What is the best measure of the population at risk?
multiplication of no. of people observed and the no. of years of observation. What is this called?
person-time at risk/no. of person-years (p-y)
what calculation gives the incidence rate?
incidence rate = no. of new cases/no. of person-years (no. of persons at risk in a specified time interval).
What is this a measure of?
individual risk - how many cases per year, per head of population
what is the mortality rate?
special case of incidence, where death is measured instead of disease onset.
How would you calculate the (point) prevalence?
no. of sufferers/no. at risk
What affects prevalence of a disease?
death, recovery, incidence
What is the calculation for prevalence when incidence rate and rate of recovery & death are constant?
P = I x L (approx. equal to)
I: incidence rate
L: mean duration of disease
What is an incidence rate ratio (IRR) used for?
compare incidence rates in 2 groups. rateA/rateB - if >1, what does this suggest?
group A is at higher risk than group B
if the mortality rate ratio comparing patients on a new treatment with those on existing treatment is <1, what does this mean?
Suggests the new treatment is associated with a reduced risk of death.
What is a confounding variable?
an extraneous variable that correlates (positively or negatively) with both the dependent variable and the independent variable.
What does indirect standardisation produce?
a ratio of the observed events to the expected from some comparator in a single population
what does direct standardisation produce?
a rate which can be compared with other rates standardised in the same way.
What is the standardised mortality ratio (SMR)?
a summary figure describing the mortality experience of a local population compared with a standard reference population, which takes into account the confounding influences of age & sex.
The standardised morbidity ratio is used for disease events rather than death.
How do you calculate SMR?
SMR = (observed deaths/expected deaths) x100
What 4 bits of info do we need to measure disease?
1 definition of a case
2 no. of cases (numerator)
3 size of at risk pop. (denominator)
4 time period
How would you calculate the ratio (relative risk) of disease?
measure in exposed group/measure in unexposed group
What are the 3 types of relative measures of exposure effect?
rate, risk & odds ratio. When do they yield similar estimates of relative risk?
When diseases are rare