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18 Cards in this Set

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~Active against some strains of MRSA
~infections caused by Pcn resistant organisms including :
-Endocarditis
-Necrotizing Fasciitis
Vancomycin

Tx-s
2ct: +2
~MRSA
~Pcn Resistant Organisms including:
-Endocarditis
-Necrotizing Fasciitis
Must be administered
-parenterally

unless you are treating
- C. Diff
Vancomycin

-Must be administered?

-Unless you are treating?
-Parenterally

- C. Diff
Class of Rx used for :

-Aerobic Gram (-) bacilli
&
-Prophylaxis Tx of Serious Infections

Can cause
-Nephro Toxicity
-Oto Toxicity
Aminoglycosides

Name Rx?

Used for what class of Organism?
Used for what kind of infect & how?

Can cause ?
Gentamycin

-Aerobic Gram (-) bacilli
-Prophylaxis Tx of Serious Infections

-Nephro Toxicity
-Oto Toxicity
-Poorly absorbed from gut

-must be used parenterally to tx systemic infections
Aminoglycosides

T or F: Aminoglycosides are absorbed well in the gut.

Route for - systemic infections?

Nm Specific Rx:
Nm the other Rx from this Class?
-Poorly Absorbed
-Parenterally


-Gentamycin

What class is it?

-Neomyacin
What aminoglycoside is the most nephrotoxic?
Neomycin

What class?
aminoglycoside
-Broad Spectrum
-Bacteriostatic
-Rx Class ?
-inhibits growth of:

Gram +
Gram -

-Chlamydiae ( G+ )
-Mycoplasmas ( G- )
-Rickettsiae ( G- )
-Spirochetes ( G- )
Tetracyclines

Static or Cidal?

Covers what classes of Gram organisms?

covers what Bugs 4ct
List their Gram classification.
-Bacteriostatic
(Inhibit Growth of)

Gram positive
&
Gram negative

Bugs:

-Chlamydiae ( G+ )
-Mycoplasmas ( G- )
-Rickettsiae ( G- ) Rocky Mtn spotted fever
-Spirochetes ( G- ) (Borrelia) Lime Dz & Relapsing fever
Use of __________(Rx) w Aminoglycosides
potentiates Nephrotoxicity
Tetracyclines

Using w _____ ? (Class Rx)...
….Potentiates _____ toxicity?
-Aminoglycosides

-Nephrotoxicity
Which Rx class causes

-Hepatotoxicity
-Photosensitivity?
Tetracyclines

This class causes?
2ct


Nm The 3 Rx?
-Hepatotoxicity
-Photosensitivity?



Doxycycline
Minocycline
Tetracycline

Nm their Class?
What Rx class

-Doxycycline
-Minocycline
Tetracyclines

Name Rx 3ct
-Doxycycline
-Minocycline
-Tetracyclines
What Class is active against::

~URIs~
-Chlamydiae M.
-Legionella Pneumophila
-Group A Strep Pneumonia
-Pneumococcal Pneumonia
Macrolides



Nm Rx 3ct?
Name Bugs 5ct:
Azithromycin
Clarithromycin
Erythromycin


~URIs~
-Chlamydiae M.
-Legionella Pneumophila
-Group A Strep Pneumonia
-Pneumococcal Pneumonia
Bacteria achieve resistance to these Rx by decreasing their binding to the 50s ribosomal subunit

Nm Class?
Macrolides

Name them 3ct?
By how?
-Azithromycin
-Clarithromycin
-Erythromycin


-by decreasing their binding to the 50s ribosomal subunit
Most commonly used agents to treat gram neg orgs
because they have become resistant to
-beta lactams
-fluoroquinolones
Aminoglycosides

This Rx is the most commonly used Rx, to treat what class of Bug?
Resistant Gram (-) Bugs
Binds to motilin and causes GI upset
Erythromycin

S/E is?
GI upset
Rx used to Tx:

-Bronchitis
-CAP
Telithromycin

Nm class?

Nm Bugs?
9ct
Ketolides


-Bronchitis
-CAP
-Chlamydia
-H. flu
-Legionella
-Moraxella Catarrhalis
-pneumoniae
-Sinusitis
-Strep
-Prolongs QT Intervals

-Increased Weakness In Myesthesia Gravis
Telithromycin

What class?

2 A/E?
Ketolides

-Prolongs QT Intervals
-Increased Weakness In Myesthesia Gravis
Active against:
Gram + cocci.

Useful in Tx infections caused by:

~MRSA
~Gram + cocci
~Anaerobes resistant to:
-Penicillin
-Other Resistive Rx-s
Clindamycin


-Active against:
-Useful in Tx infections caused by:
4ct
Gram + cocci.


~MRSA
~Gram + cocci
~Anaerobes resistant to:
-Penicillin
-Other Resistive Rx-s
Causes a higher incidence of pseudomembranous colitis

(from C-Diff superinfection)
than do other Abx.
Clindamycin

Causes What?
Causes a higher incidence of pseudomembranous colitis
Active against :

-streptococci
-staphylococci.

Administered:
Topical Tx :
-Impetigo
-Eradicate nasal carriers of MRSA
(methicillin-resistant staphylococci)
Mupirocin


Active against :?

Tx-s What?
2ct……..
….How is it administered?
-streptococci
-staphylococci.

Topical Tx :
-Impetigo
-Eradicate nasal carriers of MRSA