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36 Cards in this Set

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Cells of Intestinal epithelium

6ct
1. enterocytes or absorptive cells
2. enteroendocrine cells.
3. goblet cells
4. M (microfold) cells
5. Paneth cells
6. Stem cells
Intestinal epithelium is what type of epithelialum =
a simple columnar epithelium
what 3 celltypes are found in the crypts of Lieberkühn =

H+
Enteroendocrine 
Paneth 
Stem cells
Enteroendocrine
Paneth
Stem cells
E
D
SC
Absorptive intestinal cells aka =
enterocytes
enterocytes aka =
Absorptive intestinal cells
enterocytes
with a prominent ____ ______
also called a ____ _____
brush border
striated border

ending on a clear zone, called the _______ __________
terminal web
brush border
contains _________ microvilli
surface area 30-fold.
3000
brush border, contain
enzymes =
3ct
-lactase
-maltase
-sucrase

reduce carbohydrates to hexoses
transported
by carrier proteins
Final breakdown of oligopeptides, initiated by the action of
gastric pepsin

, is extended by pancreatic . 4ct
pancreatic trypsin,
chymotrypsin
elastase
carboxypeptidases A and B.
Malabsorption syndromes
Anemia occurs when vitamin =
B12, iron, and other cofactors cannot be absorbed.
Malabsorption syndromes
Disturbances of the musculoskeletal system
when =
proteins
calcium
vitamin D
fail to be absorbed.
A typical clinical feature of malabsorption syndromes is
diarrhea
Goblet cells are columnar
Mucus-secreting cells
In addition to its digestive function, the gastrointestinal tract is the largest diffuse
endocrine gland
in the body.
Paneth cells
have a lifetime of about
20 days.
The pyramid-shaped Paneth cells have a basal domain containing the
rough endoplasmic reticulum
three major products contained in the granules of Paneth cells are
TNF-α

lysozyme

proteins known as
defensins or cryptidins
M (microfold) cells
overly =
Peyer's patches
large intestine is formed by several successive segments
cecum
the appendix

ascending
transverse
descending
sigmoid
rectum
anus
Large Intestine
Except for the rectum, anal canal
exhibits three thickened, equally spaced bands known as =
teniae coli.


sacculations known as =
haustra
Plicae circulares and intestinal villi are not found beyond the =
ileocecal valve

The mucosa has a smooth surface.
crypts of Lieberkühn are characteristic of the mucosa of the =
colon
straight tubular intestinal glands
crypts of Lieberkuhn
Large Intestine

The surface epithelium and the epithelium lining the glands is of
simple columnar type
The lamina propria is rich in
lymphoid cells
GALT

is related to the abundant bacterial population of the large intestine.
muscularis comprises longitudinal and circular strands. This layer differs from that of the small intestine, because fibers of the outer longitudinal layer congregate in three thick longitudinal bands called ___ ___ =
teniae coli.
evagination of the cecum
APPENDIX
has abundant lymphoid follicles in its wall.

has no teniae coli.
**Cancer of the Digestive Tract:

90–95% of malignant tumors of the digestive system are derived from =
intestinal or gastric epithelial cells.
Malignant tumors of the large bowel are derived almost exclusively from its glandular epithelium =
adenocarcinomas

the second most common cause of cancer deaths in the United States.
rectum is the dilated portion
presence of folds called
transverse rectal folds

mucosa is similar to that of the
distal colon.
The upper part of the anal canal has longitudinal folds called the
anal columns.
The anal canal is divide into three zones =
1 Colorectal zone
2 Anal transitional zone
3 Squamous zone
The mucularis mucosae disappears at the =
anal transitional zone ATZ.
There is no teniae coli in
rectum
circular muscle layer of the muscularis externa thickens to form the
internal anal sphincter.
external anal sphincter is formed by
striated muscle of the pelvic floor.

pic info +