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16 Cards in this Set

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***
BULK TRPT is endo or exo =
Endocytosis = 3 types =
Fluid phase pinocytosis:
Receptor mediated endocytosis:
Phagocytosis:
Fluid phase pinocytosis: uses a =
Pinocytotic vesicle
is it a Bulk Trpt =
YES
Receptor mediated endocytosis: uses a =
coated vesicle
is it a Bulk Trpt =
YES
Phagocytosis uses a =
phagosome
(scan for nonself)
engulf
&
degrade
by enzymatic process.

is it a Bulk Trpt =
YES
Pino means what in Gk
(Gr = drinking)
Exocytosis = Things going out
Has 2 pathways
~Constitutive Secratory Pathway means what =

~Regulated Secretion Pathway ie =
(Constitutive = means always)

(Insulin any stored proteins)
Plasma Membrane Fctn =
2ct
1) Selective barrier = describe

2) Communication = describe
– semipermeable membrane: regulates cell content / volume

a. messages from outside of cell to inside (hormones, etc.)
b. messages between cells (Gap Junctions)
nfo: Membrane proteins are excellent targets for
Chemotherapeutic Rx
Signal Receptor 4ct =

A
P
E
S
Autocrine signal
Paracrine signal
Endocrine signal
Synaptic signal

Describe each =
a: Autocrine signaling: chemical mediators acts on the cell that produced it.

b: Paracrine signaling: chemical mediators secreted from one cell & acts on adjacent cells.


c: Endocrine signaling: hormone discharged into blood and transported to effector cell.


d: Synaptic signaling: neurotransmitter act only on adjacent nerve cells through synapse.
a- Autocrine signal
describe =
signals itself)
b- Paracrine signal
describe =
(signals a neighbor or passer by…something close)
c- Endocrine Signal
describe =
Hormone mediated …discharges hormone in heme...
Trpt to target effector
d- Synaptic signal
describe =
(neurotransmitter act only on adjacent nerve cells through synapse )
Signal Receptors for PM
2 classification =
Hydrophobic Signaling =
Hydrophilic Signaling =
Steroid / Hormone (They pass through the plasma membrane)


G Proteins because they bind to Guanine Nucleotides
Ligand bind to receptor ---- >
change confirmation --- >
transcription Fctr --- >
change expression
(or not depending on cell)
Different steps in signaling can cause same =
Dz