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43 Cards in this Set

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primitive gut tube is formed during
4th week
primitive gut tube is formed from incorporation of the dorsal part of the
yolk sac

into the embryo as a result of the =
craniocaudal and lateral folding of the embryo
The primitive gut tube extends from the
oropharyngeal membrane to the cloacal membrane
and is
divided into the foregut, midgut, and hindgut.
***
Know it all 
fore
mid
hind
***
Know it all
fore
mid
hind
Early in development, the epithelial lining of the gut tube proliferates rapidly and obliterates the lumen. Later, recanalization occurs.
Early in development, the epithelial lining of the gut tube proliferates rapidly and obliterates the lumen. Later
recanalization occurs.
Mucosa Epithelial Lining of glands Derived from =
Endoderm
Endoderm
Mesoderm Derives what =
5ct
..
..
Oropharyngeal membrane / stomodeum

6.Cloacal membrane / proctodeum

Come from
Ectoderm  (an Exception)
Ectoderm (an Exception)
FOREGUT gives rise to:****
pharynx
lower respiratory system
esophagus and stomach
duodenum (proximal
liver *
pancreas *
biliary apparatus *
Esophagus develops from the ________ immediately caudal to the pharynx .
foregut

+
The foregut is divided into the esophagus dorsally and the trachea ventrally by the tracheoesophageal folds, which fuse to form the tracheoesophageal septum.
diverticulum becomes separated from the primitive pharynx by trachoesophageal folds which fuse to form the
trachoesophageal septum, 
dividing the foregut into  laryngotracheal tube 
esophagus
trachoesophageal septum,
dividing the foregut into laryngotracheal tube
esophagus
stratified squamous epithelium
mucosal glands
submucosal glands
of
esophagus
are derived from
endoderm
lamina propria
muscularis mucosae
submucosa
skeletal muscle
smooth muscle of muscularis externa
adventitia of the esophagus
derived from visceral
mesoderm
Esophageal atresia :
occurs when the
tracheoesophageal septum deviates too far dorsally
causing the esophagus to end as a closed tube.

+
The esophagus is divided into two pouch blind, an upper and lower, which may or may not communicate with the tracheobronchial tree.
About 33% of patients with esophageal atresia have other congenital defects associated with the
VATER
VACTERL
VATER (vertebral defects, anal atresia, tracheoesophageal fistula, and renal defects) or

VACTERL (similar to VATER but includes cardiovascular defects and upper limb defects) syndromes.
Esophageal atresia is associated clinically with =
tracheoesophageal fistula.
esophageal atresia S/S:
unable to swallow its own saliva
gastric distention
cough, apnea/SOB
tachypnea
cyanosis
#1 Incomplete Recanalization

#2 Myo Extra Hypertrophy

#3 Membronous Diapragm
Reasons for Esophogeal Atresia
esophageal atresia
Diagnosis
This condition is visible, after about
___ weeks

T/F
a feeding tube will not pass through the esophagus.
26 weeks

True
esophageal atresia
Complications
-aspiration pneumonia

-fistula between the lower esophagus and trachea
If associated with TEF---Abdominal distention after crying
.Reflux of gastric contents into lungs, causing pneumonitis.
Diagnostic feature is =
Diagnostic features include inability to pass a catheter into the infant's stomach
Esophageal stenosis :
occurs when the =
lumen of the esophagus is narrowed and usually involves the midesophagus.
Esophageal stenosis
stenosis may be caused by
-submucosal/muscularis externa hypertrophy,

-emnants of the tracheal cartilaginous ring within the wall of the esophagu

-#1 Cause
incomplete recanalization...
(membranous diaphragm obstructing the lumen )
Esophageal diverticulum:
a pouch that protrudes outward in a weak portion of the esophageal lining.
Esophageal diverticulum:

Esophageal diverticula are classified by their location within the esophagus:
Zenker’s
Midthoracic
Epiphrenic
Esophageal diverticulum:
Zenker’s diverticula
most common
located in the back of the throat
above the esophagus
Esophageal diverticulum:

Midthoracic diverticula
mid-chest
Esophageal diverticulum:

Epiphrenic diverticula
above the diaphragm
. Esophageal hiatal hernia :
herniation
into the pleural cavity caused by an abnormally large esophageal hiatus.
An esophageal hiatal hernia renders the esophagogastric sphincter =
incompetent
►Omentum : fold of peritoneum extending from the
stomach to adjacent abdominal organs.
stomach to adjacent abdominal organs.
EnteroEndocrine Hormones
are from Endoderm

the exception is = 2ct
Enterochromaffin Cells

Enterochromaffin Like Cells (ELC)

Which come from ___________ Cells
Derived from ___ =
Ectoderm (NCC)
The primitive gut tube extends from the
oropharyngeal mem =
3ctbrane to the cloacal membrane
foregut
, midgut,
hindgut.
Embryologically, the epithelial lining and glands of the mucosa are derived from
endoderm


whereas the other components are derived from -
visceral mesoderm.
____________ an invagination of the surface ectoderm of the embryo, at the point where later the mouth is formed.
Stomodeum
: is the back ectodermal part of an alimentary canal.

It is created during embryogenesis by a folding of the outer body wall
Proctodeum
the trachoesophageal septum, dividing the foregut into =
laryngotracheal tube
esophagus
The stratified squamous epithelium, mucosal glands, and submucosal glands of the esophagus are derived from
endoderm
The lamina propria, muscularis mucosae, submucosa, skeletal muscle and smooth muscle of muscularis externa, and adventitia of the esophagus are derived from visceral
mesoderm
Name the structures comes from the Primordial
Forgut
Midgut
Hind gut
Forgut
esophagus
stomach
liver
gallbladder
pancreas
upper duodenum


Midgut
lower duodenum
jejunum
Ilium
Secom
appendix
ascending:
proximal 2\3 transverse colon
Hind gut
Distal1/3 transverse colon
Descending
Sigmoid
Rectum
upper anal canal
Name the structures comes from the Primordial Hindgut

5
Distal1/3 transverse colon
Descending
Sigmoid
Rectum
upper anal canal
Name the structures comes from the Primordial Midgut
7
lower duodenum
jejunum
Ilium
Cecum
appendix
ascending:
proximal 2\3 transverse colon
Name the structures comes from the Primordial Forgut
6
esophagus
stomach
liver
gallbladder
pancreas
upper duodenum