Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/21

Click to flip

21 Cards in this Set

  • Front
  • Back
Cytochalasin B
Bind to + end prevents elongation
- shrinks to Cc-
- doesn't affect muscle

Cap Z
Phalloidin
binds at interface between subunits, prevents depolymerization

- stabilizes
- change rates at both ends
- ATP hydrolysis irrelevant

-tropomyosin
Latrunculin
sequesters, changes the shape


- thymosin b4
thymosin B4
sequesters, binds to ADP form


- latrunculin
Profilin
sequesters, promote poly at + end

- exchanges ATP for ADP
- promotes binding to + end with high affinity
Cofilin (ADF)
promotes dissembly at -


- bound middle causes stress and severing
LIM Kinase
phosphorlyates ADF and promotes function
PIPII
binds ADF and profilin and inactivates them
VASP
bind profilin and localizes them
Tropomodulin
capper at - end
Cap Z
capper at + end


- cytochalsin B
Tropomyosin
stabilizes actin in muscle

- phalloidin
ARP 2/3
template at - end, outgrowth

- regulated by WASP, needed to activate
Formins
nucleator, + end and promote addition of new subunits

-prevents capping
- poly at + end
Fimbrin
Cross link, two ABD and spacer

- stiff bundles
- calmodulin subunit binds ca2+, activates
Filamin
Mesh work, cross linker, more floppy
-calmodulin unit
Gelsolin
cuts crosslnks, binds + end


- ADF
a- actinin
semi-stif bundles, dimer, tails interact can wilgge alittle bit but not as much as filamin
Titin
spring that holds the myosine
nebulin
molecular ruler, binds to actin and wraps along entire thin filament
Troponin Complex
binds tropomyosin, 3 subunits, TIC

- as CA2+ rises, triggers shape change in troponin, causes tropomyosine to move and allows myosine to bind