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118 Cards in this Set
- Front
- Back
Influenza is caused by the.......
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Influenza Virus
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Virus that is enveloped and keeps on changing?
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Cause: Influenza Virus
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Viral diseases of the respiratory tract include ....
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Influenza and the Common cold
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Cuase of Influenza is also because of
1. 2. 3. |
Antigenic Variation
Antigenic shift Antigenic drift |
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Antigenic Variation-
Antigenic Shift- Antigenic Drift- |
Swap genetic info between diff. species
human-bird-pig 2. sometimes 3. drift all the time |
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Symptoms: Fever, muscle aches myalgia, sneezing, coughing
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Influenza Symptoms
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Cause of major pandemic in 1918.
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Flu
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Complications of influenza...
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Immunosuppressive
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Treatment for influenza....
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Amantadine, Rimantodine, Relenza & Tamiflu
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Prevention for influenza...
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Influenza vaccine
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For the common cold there are 200 different types of Viruses, including...
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The most common
Rhinoviruses Coronaviruses |
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symptoms are variable and include....
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Nasal obstruction, Nasal discharge and sneezing most common..... NO FEVER !
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Viral diseases of the lower respiratory tract
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CROUP ( acute larynogotracheobronchitis)
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Parainfluenza Virus is the cause of
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CROUP
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Pathogenesis of CROUP...
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Virus travels from upper to lower respiratory tract
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Breathing difficulty and Hoarse BARKING cough but not that dangerous with children.
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Symptoms of CROUP
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List the differences of the common cold and the flu.
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...
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General concept of Viral diseases of the skin...
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Different paths through the body.
From Contact, Blood, or Nerves---- to the skin. |
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Symptoms of Viral diseases of the skin.
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-Macules
-Papules -& Vesicles |
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Herpes infection HSV-1 and HSV-2.
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Often asymptomatic
General symptoms--- Vesicle- Ulcer-Crust- |
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Herpes is infamous for its ability to hid within the body known as ...
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Latency
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Virus filled blister
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Vesicle
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Thickening of skin, sticks up, ex. would be a wart
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Papules
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little red spots, rashes,
ex. measles. |
Macules
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-usually caused by HSV-1
-PRIMARY Infection -seen in children -Lesions around mouth NOT LIFE THREATENING |
Herpetic Gingivostomatitis
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Usually caused by HSV-1
- RECURRENT Infection -Latent in _______ ______. -Symptoms Lesions around mouth |
Recuurent Infection that is latent in the Trigeminal Nerve.
Herpes Labialis |
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This viral disease of the eye is caused by Auto innoculation where..
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Itch cold sore on mouth then itch your own eye.
(Herpes Keratoconjuctivitis) |
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Symptoms include *Dendritic lesion
- Blurred vision can recur. Can cause BLINDNESS- every time it comes back form latency it causes more damage. |
(Herpes Keratoconjuctivitis)
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Cause- V aricella Zoster Virus
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Chicken Pox
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Transmission: is respiratory and CONTACT
Pathogenesis: URI- Blood- Skin |
Chicken Pox
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Ususally caused by HSV-1 and Keratitis involves cornea.
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(Herpes Keratoconjuctivitis)
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Symptoms of Chicken Pox
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-Not really fatal
-Vesicles(infection filled), and *Common Cold symptoms. |
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Complications with Chicken Pox......and Prevention..?
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Immunosuppression
Vaccine. |
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As an adult chicken pox is very severe w/out a vaccination.
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Facts
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Cause of this Viral disease of the skin is the reactivation of the latent Varicella Zoster Virus.
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Shingles
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Pathogenesis of Shingles
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Virus travels to skin along NERVE.
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Symptoms of Shingles
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Typically one time event.
Horrible NERVE pain Vesicles w/ red background w/ in Dermatome(block of skin in particular to disease) |
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The measle virus will give you the .....
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Measles
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Pathogenesis of the measles virus
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URI--Blood--Skin
Maculopapular rash. |
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Complications w/ the Measles
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Significantly immunosuppression, neurological infections from no treatment and no drugs
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Prevention for Measles----
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MMR vacination
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The Rubella Virus causes---
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The Rubella--German Measles
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pathogenesis for Rubella is the same as measles
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URI--Blood--Skin
Maculopapular Rash |
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Complications with Rubella...
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Congenital Rubella, low birth weight & defects of the eye, ears and heart.
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Prevention of Rubella is the same as Measles---
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MMR vacination
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The cause of Warts is the the ----
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Papilloma Virus (HPV)
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Transmission of HPV
Pathogenesis of HPV |
Contact &
Virus causes hyperplasia of the skin cells |
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Symptoms of HPV
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Papules-- Warts
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The Mumps is caused by the ....
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Mumps Virus in the salivary glands
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Pathogenesis of the Mumps
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Srats as URI--Blood-- then to various organs
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Symptoms of Mumps
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Swollen paritid glands
Orchitis in adult males - Pain in the testes |
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Prevention for the Mumps
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MMR vaccine
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Hepatitis A
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Mild disease, low fatality and cause is the Hepatitis A Virus (HAV)
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Transmission for HAV
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Enteric
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Syptoms of HAV
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-Asymptomatic or Jaundice
-Abdominal discomfortand -Mild anorexia |
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Prevention of HAV
(from contaminated food and water) |
-Good hygeine
-Passive immunization -Vaccine |
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Cuase of Hepatitis B Virus
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Serum of infected person contains viruses and viral particles
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Numbers are huge--
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up to a trillion per milliter of blood
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Transmission of HBV
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-Blood & Blood products,
-Sexual contact STD -Mother to child thru placenta |
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Facts of HBV
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-There is a 80% recovery and the 1% of people who get it will die.
-Some have chronic Hepatitis B |
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Symptoms of HBV
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Acute or chronic Infection
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Compications with HBV & Treatment
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-Liver cancer &
-(dangerous) Alpha Interferon treatment |
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Prevention for HBV
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Component Vaccine
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Transmission of HCV
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Blood and Blood produtcs
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Symptoms of HCV
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High incidence of chronic disease leading to chirrosis of the liver
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Treatment for HCV
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Alpha Interferon
30 to 50% stay within the body. |
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Another way to get Hepatitis B & C is with...
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Tattoos and Body piercings
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Delta Hepatitis is caused by....
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Delta particle (defective Virus)
- requires more co-infection w/ Hepatitis B Virus |
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Symptoms with Delta Hepatitis are more....
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Severe
-You cant get Delta Hepatitis w/out Hepatitis B. |
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-The cause of Hepatitis E is the ...
-Transmission is.. -Symptoms? |
-Hepatitis E Virus (HEV)
-Enteric - High Mortality |
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Hepatitis G cause...
-Transmission -Symptoms? |
HGV
-Blood - are Mild |
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Viral Gastroenteritis
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-Caused by the Rotavirus or the Norwalk family of viruses(AKA noroviruses)
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Viral Gastroenteritis
-Symptoms? -Prevention & Treatment? |
very common disease
-diarrhea -good hygiene while there is a vaccine under study |
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Viral diseases of the Digestive System
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-Mumps
-Viral Hepatitis (A,B,C,D,E,G) -Viral gastroenteritis |
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Viral Diseases of the Skin and Eyes
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-Herpetic Gingivostomatitis
-Herpes Labialis -Chicken Pox (Varicella) -Shingles -Measles -Rubella -Warts |
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Viral diseases of the Nervous System
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-Rabies
-Viral Encephalitis -Guillain-Barre' Syndrome -Reyes Syndrome |
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Transmission of the Rabies virus
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Saliva
Disease of animals(just mammals) |
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pathogenesis of Rabies
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Peripheral Nerves -->CNS-->
Salivary glands-->Destroys Neurons |
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Rabies Treatment?
Prevention? |
-Vaccine, Immnunization
-Vaccine, or 100% fatality rate *You have 1 month of keeping virus out of CNS |
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Arbooviral encephalitis
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Encephalitis caused by mosquito-bourne viruses
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Cause of Arboviral Encephalitis?
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Many & including West Nile encephalitis
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Transmission of ARBO
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By mosquitos, hosts are small mammals and birds
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Symptoms of ARBO?
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-Range from mild to -->
Convulsions or seizures- *Often high fatality rate |
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Syndrome?
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A set of symptoms w/out known cause.
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Cause: Associated w/ certain Viral Infections
Mechanisms: possibly Auto Immune Symptoms: Progressive paralysis |
Guillain Barre' Syndrome
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-Cause: associated w/ certain viral infections
-Symptoms: damage to brain and liver* Can be fatal |
Reye's Syndrome
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-Occurence: in children & adolescents--> assoc. w/ asprin use
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Reye's Syndrome
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Viral disseminated & cardiovascular Diseases
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-Infectous Mononucleosis
-Yellow fever -Viral Hemorrhaghic fevers -Cytomagalovirus (CMV) -*HIV |
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Cause: Epstein BARR virus
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Infectious Mononucleosis
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-Transmission: Saliva
-Symptoms: FEVER, Swollen lymph nodes, sore throat (classic), & fatigue |
Infectious Mononucleosis
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Cause: yellow fever virus
Transmission? Symptoms? |
-Mosquito
-Jaundice, FEVER |
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AKA Hepatitis D
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Delta Hepatitis
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Common member of the Herpesvirus Family
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Cytomegalovirus (CMV)
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-Common virus usually asymptomatic
-Serious disease primarily seen in: Infants & Immunosuppressed |
Cytomegalovirus (CMV)
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HIV is caused by HIV-1 and HIV-2
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HIV-1 more deadly
HIV-2 found in Africa, milder disease |
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Continued HIV cause:
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-Retroviruses in the body convert RNA to--> DNA
-Surface Antigens change |
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Transmission of HIV
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-Blood and Blood products
-sexual contact -Mother to child |
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HIV mechanisms
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-From Latency when virus reactivates at times & replicates then drugs can get to it.
-Latent Virus remains in some Helper T cells & can later infect the body |
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HIV mechanisms
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Drugs cant reach Latent Virus in T cells. Leads to Loss of helper T cells and progression of disease.
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Pathogenesis of HIV
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Reproduction in Helper T cells
helper T cells are getting a double hit from virus & Tc cells attacking it. |
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patho HIV
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Helper T cells are the center of the immune system and needed to activate other cells
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patho HIV
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Frequent Viral and parasitic infections due to no Helper T cell activation.
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patho HIV
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Tuberculosis common due to collaspe in Immune system
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Treatment HIV
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-Various drugs
Protease Inhibitors -AZT, ddI, ddC |
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Prevention HIV
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-Safe sex and vaccines under study
****hard to get vaccine due to changing antigens and virus that attaches to Immune system |
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Viral Genitourinary Diseases
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-Genital Herpes
-Genital Warts |
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Complications with HSV-2
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Neonatal Herpes
*exposure to herpes during pregnancy *or can be infected through the placenta, *or thru birth canal |
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Treatment for HSV-2
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Acyclovir
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Cause: HSV-2
Symptoms: Vessicles(fluid filled), erupt--> crust over. Reactivates. Latency |
HSV-2
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Cause: Certain papilloma viruses
Symptoms: Warts |
Genital Warts
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Complications with Warts
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Cervical Cancer
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Treatment?
Prevention? |
-Surgery, interferon
-Safe sex, Vaccine |
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The transmission of herpetic Keratoconjuctivitis involves....
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contact (auto innoculation) from a lesion elsewhere in the body
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Rabies has a long incubation period because?
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the virus travels slowly up the peripheral nerves to the spinal cord
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Difficult breathing and Hoarse barking are signs or symptoms of?
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CROUP
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This Virus causes the death of helper T cells
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HIV
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Eating or drinking water that was contaminated by human feces might lead to infection by....
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Hepatitis A or B
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A combination of damage to the liver, kidneys, and CNS is due to
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Yellow Fever
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