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118 Cards in this Set

  • Front
  • Back
Influenza is caused by the.......
Influenza Virus
Virus that is enveloped and keeps on changing?
Cause: Influenza Virus
Viral diseases of the respiratory tract include ....
Influenza and the Common cold
Cuase of Influenza is also because of
1.
2.
3.
Antigenic Variation
Antigenic shift
Antigenic drift
Antigenic Variation-
Antigenic Shift-
Antigenic Drift-
Swap genetic info between diff. species
human-bird-pig
2. sometimes
3. drift all the time
Symptoms: Fever, muscle aches myalgia, sneezing, coughing
Influenza Symptoms
Cause of major pandemic in 1918.
Flu
Complications of influenza...
Immunosuppressive
Treatment for influenza....
Amantadine, Rimantodine, Relenza & Tamiflu
Prevention for influenza...
Influenza vaccine
For the common cold there are 200 different types of Viruses, including...
The most common
Rhinoviruses
Coronaviruses
symptoms are variable and include....
Nasal obstruction, Nasal discharge and sneezing most common..... NO FEVER !
Viral diseases of the lower respiratory tract
CROUP ( acute larynogotracheobronchitis)
Parainfluenza Virus is the cause of
CROUP
Pathogenesis of CROUP...
Virus travels from upper to lower respiratory tract
Breathing difficulty and Hoarse BARKING cough but not that dangerous with children.
Symptoms of CROUP
List the differences of the common cold and the flu.
...
General concept of Viral diseases of the skin...
Different paths through the body.
From Contact, Blood, or Nerves---- to the skin.
Symptoms of Viral diseases of the skin.
-Macules
-Papules
-& Vesicles
Herpes infection HSV-1 and HSV-2.
Often asymptomatic
General symptoms---
Vesicle- Ulcer-Crust-
Herpes is infamous for its ability to hid within the body known as ...
Latency
Virus filled blister
Vesicle
Thickening of skin, sticks up, ex. would be a wart
Papules
little red spots, rashes,
ex. measles.
Macules
-usually caused by HSV-1
-PRIMARY Infection
-seen in children
-Lesions around mouth
NOT LIFE THREATENING
Herpetic Gingivostomatitis
Usually caused by HSV-1
- RECURRENT Infection
-Latent in _______ ______.
-Symptoms Lesions around mouth
Recuurent Infection that is latent in the Trigeminal Nerve.
Herpes Labialis
This viral disease of the eye is caused by Auto innoculation where..
Itch cold sore on mouth then itch your own eye.
(Herpes Keratoconjuctivitis)
Symptoms include *Dendritic lesion
- Blurred vision can recur.
Can cause BLINDNESS- every time it comes back form latency it causes more damage.
(Herpes Keratoconjuctivitis)
Cause- V aricella Zoster Virus
Chicken Pox
Transmission: is respiratory and CONTACT
Pathogenesis: URI- Blood- Skin
Chicken Pox
Ususally caused by HSV-1 and Keratitis involves cornea.
(Herpes Keratoconjuctivitis)
Symptoms of Chicken Pox
-Not really fatal
-Vesicles(infection filled), and *Common Cold symptoms.
Complications with Chicken Pox......and Prevention..?
Immunosuppression
Vaccine.
As an adult chicken pox is very severe w/out a vaccination.
Facts
Cause of this Viral disease of the skin is the reactivation of the latent Varicella Zoster Virus.
Shingles
Pathogenesis of Shingles
Virus travels to skin along NERVE.
Symptoms of Shingles
Typically one time event.
Horrible NERVE pain
Vesicles w/ red background w/ in Dermatome(block of skin in particular to disease)
The measle virus will give you the .....
Measles
Pathogenesis of the measles virus
URI--Blood--Skin
Maculopapular rash.
Complications w/ the Measles
Significantly immunosuppression, neurological infections from no treatment and no drugs
Prevention for Measles----
MMR vacination
The Rubella Virus causes---
The Rubella--German Measles
pathogenesis for Rubella is the same as measles
URI--Blood--Skin
Maculopapular Rash
Complications with Rubella...
Congenital Rubella, low birth weight & defects of the eye, ears and heart.
Prevention of Rubella is the same as Measles---
MMR vacination
The cause of Warts is the the ----
Papilloma Virus (HPV)
Transmission of HPV
Pathogenesis of HPV
Contact &
Virus causes hyperplasia of the skin cells
Symptoms of HPV
Papules-- Warts
The Mumps is caused by the ....
Mumps Virus in the salivary glands
Pathogenesis of the Mumps
Srats as URI--Blood-- then to various organs
Symptoms of Mumps
Swollen paritid glands
Orchitis in adult males
- Pain in the testes
Prevention for the Mumps
MMR vaccine
Hepatitis A
Mild disease, low fatality and cause is the Hepatitis A Virus (HAV)
Transmission for HAV
Enteric
Syptoms of HAV
-Asymptomatic or Jaundice
-Abdominal discomfortand
-Mild anorexia
Prevention of HAV
(from contaminated food and water)
-Good hygeine
-Passive immunization
-Vaccine
Cuase of Hepatitis B Virus
Serum of infected person contains viruses and viral particles
Numbers are huge--
up to a trillion per milliter of blood
Transmission of HBV
-Blood & Blood products,
-Sexual contact STD
-Mother to child thru placenta
Facts of HBV
-There is a 80% recovery and the 1% of people who get it will die.
-Some have chronic Hepatitis B
Symptoms of HBV
Acute or chronic Infection
Compications with HBV & Treatment
-Liver cancer &
-(dangerous) Alpha Interferon treatment
Prevention for HBV
Component Vaccine
Transmission of HCV
Blood and Blood produtcs
Symptoms of HCV
High incidence of chronic disease leading to chirrosis of the liver
Treatment for HCV
Alpha Interferon
30 to 50% stay within the body.
Another way to get Hepatitis B & C is with...
Tattoos and Body piercings
Delta Hepatitis is caused by....
Delta particle (defective Virus)
- requires more co-infection w/ Hepatitis B Virus
Symptoms with Delta Hepatitis are more....
Severe
-You cant get Delta Hepatitis w/out Hepatitis B.
-The cause of Hepatitis E is the ...
-Transmission is..
-Symptoms?
-Hepatitis E Virus (HEV)
-Enteric
- High Mortality
Hepatitis G cause...
-Transmission
-Symptoms?
HGV
-Blood
- are Mild
Viral Gastroenteritis
-Caused by the Rotavirus or the Norwalk family of viruses(AKA noroviruses)
Viral Gastroenteritis
-Symptoms?
-Prevention & Treatment?
very common disease
-diarrhea
-good hygiene while there is a vaccine under study
Viral diseases of the Digestive System
-Mumps
-Viral Hepatitis
(A,B,C,D,E,G)
-Viral gastroenteritis
Viral Diseases of the Skin and Eyes
-Herpetic Gingivostomatitis
-Herpes Labialis
-Chicken Pox (Varicella)
-Shingles
-Measles
-Rubella
-Warts
Viral diseases of the Nervous System
-Rabies
-Viral Encephalitis
-Guillain-Barre' Syndrome
-Reyes Syndrome
Transmission of the Rabies virus
Saliva
Disease of animals(just mammals)
pathogenesis of Rabies
Peripheral Nerves -->CNS-->
Salivary glands-->Destroys Neurons
Rabies Treatment?
Prevention?
-Vaccine, Immnunization
-Vaccine, or 100% fatality rate
*You have 1 month of keeping virus out of CNS
Arbooviral encephalitis
Encephalitis caused by mosquito-bourne viruses
Cause of Arboviral Encephalitis?
Many & including West Nile encephalitis
Transmission of ARBO
By mosquitos, hosts are small mammals and birds
Symptoms of ARBO?
-Range from mild to -->
Convulsions or seizures- *Often high fatality rate
Syndrome?
A set of symptoms w/out known cause.
Cause: Associated w/ certain Viral Infections
Mechanisms: possibly Auto Immune
Symptoms: Progressive paralysis
Guillain Barre' Syndrome
-Cause: associated w/ certain viral infections
-Symptoms: damage to brain and liver* Can be fatal
Reye's Syndrome
-Occurence: in children & adolescents--> assoc. w/ asprin use
Reye's Syndrome
Viral disseminated & cardiovascular Diseases
-Infectous Mononucleosis
-Yellow fever
-Viral Hemorrhaghic fevers
-Cytomagalovirus (CMV)
-*HIV
Cause: Epstein BARR virus
Infectious Mononucleosis
-Transmission: Saliva
-Symptoms: FEVER, Swollen lymph nodes,
sore throat (classic), & fatigue
Infectious Mononucleosis
Cause: yellow fever virus
Transmission?
Symptoms?
-Mosquito
-Jaundice, FEVER
AKA Hepatitis D
Delta Hepatitis
Common member of the Herpesvirus Family
Cytomegalovirus (CMV)
-Common virus usually asymptomatic
-Serious disease primarily seen in: Infants & Immunosuppressed
Cytomegalovirus (CMV)
HIV is caused by HIV-1 and HIV-2
HIV-1 more deadly
HIV-2 found in Africa, milder disease
Continued HIV cause:
-Retroviruses in the body convert RNA to--> DNA
-Surface Antigens change
Transmission of HIV
-Blood and Blood products
-sexual contact
-Mother to child
HIV mechanisms
-From Latency when virus reactivates at times & replicates then drugs can get to it.
-Latent Virus remains in some Helper T cells & can later infect the body
HIV mechanisms
Drugs cant reach Latent Virus in T cells. Leads to Loss of helper T cells and progression of disease.
Pathogenesis of HIV
Reproduction in Helper T cells
helper T cells are getting a double hit from virus & Tc cells attacking it.
patho HIV
Helper T cells are the center of the immune system and needed to activate other cells
patho HIV
Frequent Viral and parasitic infections due to no Helper T cell activation.
patho HIV
Tuberculosis common due to collaspe in Immune system
Treatment HIV
-Various drugs
Protease Inhibitors
-AZT, ddI, ddC
Prevention HIV
-Safe sex and vaccines under study
****hard to get vaccine due to changing antigens and virus that attaches to Immune system
Viral Genitourinary Diseases
-Genital Herpes
-Genital Warts
Complications with HSV-2
Neonatal Herpes
*exposure to herpes during pregnancy
*or can be infected through the placenta,
*or thru birth canal
Treatment for HSV-2
Acyclovir
Cause: HSV-2
Symptoms: Vessicles(fluid filled), erupt--> crust over. Reactivates. Latency
HSV-2
Cause: Certain papilloma viruses
Symptoms: Warts
Genital Warts
Complications with Warts
Cervical Cancer
Treatment?
Prevention?
-Surgery, interferon
-Safe sex, Vaccine
The transmission of herpetic Keratoconjuctivitis involves....
contact (auto innoculation) from a lesion elsewhere in the body
Rabies has a long incubation period because?
the virus travels slowly up the peripheral nerves to the spinal cord
Difficult breathing and Hoarse barking are signs or symptoms of?
CROUP
This Virus causes the death of helper T cells
HIV
Eating or drinking water that was contaminated by human feces might lead to infection by....
Hepatitis A or B
A combination of damage to the liver, kidneys, and CNS is due to
Yellow Fever