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20 Cards in this Set
- Front
- Back
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What is salvia officinalis?
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Cooking sage
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Who discovered salvia divinorum?
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Gordon Wasson (1989-1986)
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What is the primary route of administration in historical use?
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Oral/buccal and fresh leaves are also chewed
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What is the major identified psychoactive component of salvia divinorum?
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Salvinorin A
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Is Salvinorin A an alkaloid?
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No
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What are the three different opoid receptor subtypes?
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-Mu
-Delta -Kappa |
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What receptor does salvinorin A bind to?
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Kappa opioid receptor
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Does salvinorin A bind with high or low specificity to the Kappa opioid receptors?
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High
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What is naloxone?
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A high affinity non-specific competitive opioid receptor antagonist
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What is bremazocine?
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A specific kappa opioid receptor ligand?
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What is the hallucinogen control act of 2002?
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-Salvia divinorum and salvinorin A would become schedule 1 controlled substances
-Proposal did not make it out of committee |
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Where did cannabis originate from?
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Central Asia
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What is the primary active psychoactive chemical in cannabis?
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Delta-9-tetrahydrocannabinol
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Who discovered THC?
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Raphael Mechoulam
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Is THC hydrophobic?
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Yes, it is an oil
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How much more potent is CP55940?
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50x more potent than THC
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What is the most abundant receptor in the brain?
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The cannabinoid GPCR receptor
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What is the endogenous cannabinoid neurotransmitter?
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Anandamide
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What does anand mean?
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Bliss
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What do people think are the roles of the cannabinoid receptors?
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Synaptic plasticity- strengthens or weakens synaptic activity
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