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14 Cards in this Set
- Front
- Back
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What is the name of opium poppies?
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Papaver Somniferum
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Where is the psychoactive component of poppy seeds found?
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In the seed pods
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What's the major source of opium?
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India
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What are some effects of opium?
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o Analgesia= numbing pain
o Anxiolytic= numbing of psychic pain o Sedation, dream like mental state o Cough suppression o Decreased intestinal motility (mediated by the digestive system) o Pupil constriction, effects mediated by the central nervous system, not really by sympathethetic. |
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What is the oral opium drug called?
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Laudanum
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Who discovered and named morphine?
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Friedrich Wilhelm Serturner
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What was the first alkaloid to be discovered?
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Morphine
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What is the difference between heroin and the poppy?
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Heroin is a modified form of the poppy, it has two acetyl groups which allow it to cross the BBB 3x more easily
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How do you get heroine from morphine?
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Morphine -->acetylation --> heroin
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What are the acute effects of opioids?
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-Depression of respiratory control centers in brain stem- slowed respiration
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Name an opioid antagonist
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Naloxone
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What is naloxone for?
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Used to treat overdose of heroine
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What can be given to opioid abusers to ween them off the drug?
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methadone
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Where is the highest and lowest binding site for opiates?
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Highest - striatum
Lowest - cerebellum |
