Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
33 Cards in this Set
- Front
- Back
|
Michaelis Menten Equation
|
V = Vmax[S]/[S] + Km
|
|
|
Km
|
Km is equal to the substrate concentration at which the reaction rate is half of its maximal value.
|
|
|
What does high and low Km indicate?
|
High Km: weak binding of the ES complex
Low Km: indicates strong binding of the ES complex |
|
|
X axis of Linweaver Burk plot
|
1/Vmax
|
|
|
Y axis of Lineweaver Burk plot
|
-1/Km
|
|
|
Turnover Number
|
Enzyme is completely saturated with substrate, then the number of substrate molecules which are converted to product
|
|
|
Competitive inhibition
|
Vmax remains constant
Km increase |
|
|
What is the function of alcohol dehydrogenase?
|
Convert ethanol to pyruvate
or its competive inhibitor Ethylene glycol to oxalic acid |
|
|
Non competitive
|
Vmax decreases
Km remains constant |
|
|
Carboxypeptidase
|
zinc containing digestive enzyme secreted by the exocrine cells of the pancreas that hydrolyzes the carboxyl terminal peptide bond of protein polypeptide chains
|
|
|
Chymotrypsin
|
Catalyzes the hydrolysis of either ester (to alcohol and an acid) or peptide bonds (amine and an acid)
|
|
|
What do nutrients enter the liver for breaking down? How do they leave? How does blood enter?
|
The hepatic portal vein is a specalized venous system that carries nutrients absorbed from the digestive tract for processing.
The hepatic vein trains the liver and carriers glucose to the rest of the body. Hepatic artery is responsible for bringing blood to the liver. |
|
|
Can muscles release glucose into the blood?
|
NO!
|
|
|
Enzyme responsible for the interconversion of pyruvate and lactate?
|
Lactate dehydrogenase
|
|
|
What does carboxylation of pyruvate form?
|
OAA
|
|
|
Why is first interval of intense excercise anaerobic respiration?
|
The oxygen supply is lower than the oxygen demand
|
|
|
Majority of circulating FA in the body and is used as important fuel source for resting muscle?
|
Oleate
|
|
|
How are insulin levels during excercise? How about glucagon?
|
Low insulin which normally promotes uptake and storage
High glucagon to promote the breakdown of glycogen |
|
|
Where is heme broken down into bilirubin?
|
Spleen
|
|
|
What is sublimation?
|
Solid to vapor
|
|
|
What does combustion require?
|
Organic compound to yield CO2 and H20
|
|
|
What does the pentose pathway produce?
|
NADH and ribose 5 phosphate
|
|
|
Carbon monoxide
|
Inhibits the electron transfer complex 4
|
|
|
Uncouplers of the ETC
|
Destroy protein gradient
|
|
|
As you move down the ETC, what happens to the reduction potential?
|
Increases
|
|
|
ATP is produced from one pyruvate
|
15
|
|
|
ATP produce from one Acetly-CoA
|
12
|
|
|
Steps in Beta-oxidation
|
Oxidation (via FAD+)
Hydration Second oxidation (via NAD+) Thiolysis |
|
|
Fates of lipid components
|
Glycerol: Glycerol 3 Phosphate --> Glycolysis
Fatty acid: Beta Oxidation |
|
|
Regulates release of fatty acids from glycerol
|
Insulin
Epinepherhine Glucagon |
|
|
In experiment, the presence of deuterium or carbon 13 should indicate what kind of analysis?
|
Mass spectrometer
|
|
|
Futile cycle
|
Also know as substrate cycle
Two metabolic pathways that run in opposite direction but have no affect other than dissipate heat. |
|
|
What body parts preferentially use fatty acids as a fuel?
|
Heart and skeletal muscle
|
