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8 Cards in this Set
- Front
- Back
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Interphase |
1. Includes G1, S, G2 2. Longest part of cycle where actively dividing cells spend 90% of their time |
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G1 Phase |
Cells create organelles for energy and protein synthesis in mitochondria, ER, Ribosomes. |
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S Phase |
1. Synthesis 2. Replicates DNA so that each daughter cell will have identical copies 3. Production of sister chromatids joined at centromere 4. 23 pairs to 46 pairs of chromosomes |
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G2 |
Prepare for mitosis, check point ensures DNA has been duplicated and cell checks to ensure there are enough organelles and cytoplasm to divide between two daughter cells. |
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M |
Mitosis (prophase, metaphase, anaphase, telophase), and cytokinesis that occurs in somatic (non-sexual) cells. |
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G1 - S Checkpoint |
1. Restriction point controlled by p53 2. Quality control point where cell determines DNA is in good enough condition for synthesis |
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G2 - M Checkpoint |
1. p53 plays role here 2. Quality control point where cell determines adequate size and if organelles have been replicated correctly to support daughter cells |
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CDK-cyclin Complex |
Activated CDK in presence of specific cyclins which phosphorylate transcription factors |
