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21 Cards in this Set

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  • Back
What constitutes an anabolic process?
Energy-requiring, biosynthesis of complex molecules
What constitutes a catabolic process?
Release energy, biodegradative
Describe the energy processes of autotrophs.
Convert light to bond energy via photosynthesis.
Is photosynthesis an anabolic or catabolic process? Provide the chemical equation.
CO2 + water + E --> Glucose (C6H2O6) + O2
Describe the energy processes of heterotrophs.
Obtain energy catabolically (mainly through glucose metabolism)
What is the chemical equation for glucose metabolism?
Glucose + O2 --> CO2 + H2O + E
How much energy is in 1 mole of ATP?
~7 Kcal
Provide the chemical equations for both types of ATP hydrolysis.
1) ATP-->ADP + Pi + E
ATP-->AMP + PPi + E
How much energy is required for the formation of ATP from ADP? What provides this energy?
~7 Kcal; from glucose degradation
Describe how electrons can be used as a means to store and transport energy. Include energy carriers.
Energy can be stores as high potential electrons which are transferred as hydride ions or hydrogen atoms in glucose oxidation.

H atoms are removed and accepted by carrier coenzymes (NAD+, NADP+, FAD) wihch transfer high potential electrons to ETC of of inner mitochondrial membrane.
List the oxidizing and reducing agents of glucose metabolism.
Oxidizing: NAD+, FAD, NADP+
Reducing: NADH, FADH2, NADPH
Where in the cell does glycolysis occur? What is the net ATP production? Outline the basic steps.
Cytoplasm; 2 ATP
Glucose + 2 ATP-->PGAL<-->Dihydroxyacetone-Pi
PGAL + 2 ADP +NAD+-->Pyruvate + 2 ATP + NADH

The pyruvate step occurs twice, as one pyruvate is only 1/2 of one glucose.
Based on oxygen conditions, what is the next step after glycolysis?
If anaerobic: fermentation
If aerobic: cell respiration
What is the purpose of fermentation? How much ATP is produced?
Must regenerate NAD+ for glycolysis to continue without oxygen; 2 ATP per glucose.
Outline the basic steps of alcohol fermentation. What organisms carry out alcohol fermentation?
Pyruvate-->CO2 + Acetaldehyde (decarboxylation) + NADH-->EtOH + NAD+

Yeast, some bacteria
Outline the basic steps of lactic acid fermentation. What organisms carry out lactic acid fermentation?
Pyruvate + NADH-->Lactic Acid + NAD+

Fungi, bacteria, human muscle cells when moderately strained
What are the physiological effects of lactic acid production?
Decreased blood pH, leads to muscle fatigue, reverse occurs after paying O2 debt
Outline the basic steps of cellular respiration. Where does cellular respiration occur? How much ATP is produced?
36-38 ATP per glucose, mitochondria, aerobic process, O2 is final electron acceptor.

Pyruvate Decarboxylation:
Pyruvate (cyto)-->Pyruvate (mito) + CoA+ NAD+-->NADH + CO2 + AcetylCoA

Citric Acid Cycle (Krebs, TCA):
OAA + acetyl CoA-->CoA + Citrate + 3NAD+ + FAD +GDP-->-->2CO2 + 3NADH + FADH2 + GTP

2 pyruvates per glucose, so occurs twice!

ETC: Inner mito membrane
ATP produced when e- transferred from NADH & FADH2 to O2 by cytochromes (e- carriers); each carrier reduced as it received e-'s
FMN = 1st molecule of ETC
CytA3 = last carrier, passes to O2
How would the absence of oxygen affect ETC?
ETC would become backlogged with electrons and NAD+ would not be regenerated. Glycolysis would be unable to continue without fermentation.
What are the 3 protein complexes that electron carriers are located in? How do they contribute to the production of ATP?
NADH dehydrogenase
b-C1 complex
cytochrome oxidase

Energy released during transfers between complexes, as NADH passes electrons, H+ atoms released into intermembrane space, accumulate, form PROTON MOTIVE FORCE, driving protons through ATP synthetases, releasing energy which is coupled to ADP phosphorylation (OXIDATIVE PHOSPHORYLATION!)
When glucose is low, what are the preferred substrates for energy? Describe how each is processed for energy purposes.
Carbs > Fats > Proteins

Carbs-->Hydrolysis-->Glucose

Fats-->Hydrolysis-->Glycerol + Fatty Acids
Glycerol-->PGAL
FAs-->Beta-oxidation-->acetyl CoA

Protein-->Hydrolysis-->AA
AA-->Deamination-->a-keto acids-->pyruvate + acetyl CoA