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9 Cards in this Set
- Front
- Back
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Fungal Amphotericin B |
Double C BHAM |
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5 flucytosine |
Triple C |
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Azoles |
Keto Muco + dermatophytosis Flu. Triple C Itra. BSC major + any other +dermatophytosis Vori. Codrug-aspergillus + alternate(candida) Posa. Only with rhizopus and candida(AIDS +salvage therapy) |
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Griseofulvin |
MOA-1. microtubule inhibit 2. Nucleic a. inhibit . St corneum. Keratin bound. Skin and hair Pk-oral to bile. St corneum. Keratin bound. Skin and hair Clinical Dermatophytes skin and hair Clinical Dermatophytes skin and hair |
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Terbinafine |
Keratin and onchomycosis |
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Echinocandin |
Caspofungin-dissemi candida Anidula- invasive candida Micafungin- mucocutaneous and bone marrow candida |
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Amphotericin ADE |
1. Injection- fever, chill, hypotension, vomit Cure- antihistamine, glucocoticoid 2. Intrathecal inject- seizure and damage 3. Dose limiting- nephrotoxic(acidosis k and mg waste) Anemia |
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Flourocytosine ADE Echinocandin Griseofulvin Terbinafine |
1.Depress, alopecia and hepatotoxic 2. IV-headache, fever, vomit, rash, flushing Micafungin- histamine release With cyclosporine- transaminases 3. Common + photosensitivity and hepatotoxic(p450- warfarin) Disulfiram like Not given with porphyrin 4. Common + taste No p450 effect 4. Common + taste 4. Common + taste No p450 effect 4. Common + taste No p450 effect No p450 effect |
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Azole ADE |
1. Common- rash git hepatotoxic Keto- cyt p450 inhibit(warfarin and cyclosporine) Posa also Also gonal and adrenal interfere(gynecomastia and infertile) Vori- not preggo and visual disturbance. |
