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19 Cards in this Set

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avg:
60% oxygen saturation corresponds to about ___mmHg PO2
40
avg:
97% oxygen saturation corresponds to about ___mmHg PO2
100
How can we shift the saturation vs PO2 curve rightward and downward?

ie, a lower sat corresponds to higher partial pressure of O2
H+ ion increase, ph decrease,
incr CO2
Incr temp
incr 2,3-BPG

(Bohr effect)
How can we shift the saturation vs PO2 curve leftward and upward?

ie, a higher sat corresponds to lower partial pressure of O2
H+ ion decrease
enzyme catalyzing:
H2O + CO2 --> H2CO3
carbonic anhydrase
What is the respiratory exchange ratio?
rate of CO2 output / rate of O2 uptake
respiratory exchange ratio?

Normals for carbohydrate and fat diets.
carb diet: R = 1.00

fat diet: R= 0.7


mixed diet: R= 0.825
3 major groups of The respiratory center
Dorsal respiratory group
Ventral respiratory group
Pneumotaxic center
"pattern" of breathing: constant inhalation.
apneustic breathing
What is the pneumataxic center
(limits inspiration and therefore can increase ventilatory frequency).
a strong pneumotaxic signal causes what breathing?
panting
respritory group that causes inspiration
dorsal
respritory group that causes expiration
ventral
when the lungs become overly inflated, the stretch receptors activate an appropriate feedback response that “switches off” the inspiratory ramp and thus stops further inspiration.
Hering-Breuer effect
Central vs peripheral receptors. Which are dominant?
central
where are peripheral receptors?
carotid bodies and aortic arch
where are central receptors?
brain, CSF
What are central recptors sensitive to?
H+ ion.

BBB does not leet H+ ion to get across, but CO2 can get across and mingle with carbonic anhydrase thus forming H+
Why are Effects of low oxygen minimal until very low levels are reached if carbon dioxide and hydrogen ion are normal? What does this mean?
central receptors

(incomplete answer)