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34 Cards in this Set
- Front
- Back
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What is the onset of breast development called?
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Thelarche
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What is the onset of adrenal androgen steroidogensis?
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Andrenarche
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When does normal puberty begin for girls?
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8 to 12 years old
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When does normal puberty begin for boys?
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9 to 14 years old
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Are hormone levels detactable in pre-puberty?
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NO
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How is GnRH released?
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In a pulsatile fashion
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What is the first exam findng in boys of puberty?
in girls? |
Testicular enlargement
breast bud development |
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Growth spurt occur at predictable
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Tanner stages
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Menstrual cylce usually occurs during what tanner stage?
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4
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First sign of puberty in boys begins at what tanner stage?
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2
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Growth sput in boys correlates with which tanner stage?
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4
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What age is considered pubertal delay in boy?
In girls? |
Boys - 14
Girls - 13 |
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Does pubertal delay mean pathology?
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NO
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What should you consider if a girl has not had menarche at 16 or started going through puberty 5 years ago?
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Pubertal delay
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What is HYPERgonadotropic hypogonadism caused by?
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Elevated gonadotropins due to gonadal failure
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What is HYPOgondtropic hypogonadism caused by?
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Inadequate function of gonads due to failure to secrete FSH or LH (deficent in GnRH)
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What are two genetic disorders resulting in HYPERgonadotropic hypogonadism?
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Turner
Klinefelter |
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What is the primary gonadal failure associated with Turner's?
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Early adrenarche
Delayed pubarche |
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What is the most common genetic cause of infertility and hypogonadsim in males?
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Klienfelter syndrome
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What is the FSH and LH levels in Klienferlter syndrome?
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High
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What is one sydrome caused by HYPOgonadotropic hypogonadims?
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Kallman's syndrome
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What is Kallman's syndrome?
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Hypothalmus does not contain GnRH cells
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Kid can't smell (anosmia) what might they have?
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Kallman's syndrome
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How do you treat Kallman's?
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HRT
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What is the age of precocious puberty in girls?
In boys? |
Girls = pubes <7 or menarche <9
Boys = pubes <9 |
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Precocious puberty is devided into 2 categories
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Central (gonadotropin dependent)
Peripheral (gonadotropin independent) |
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What is the cause of central precocious puberty in girls?
In boys? |
Girls = idiopathic
Boys = CNS pathology |
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Who should you get an MRI on with central precocious puberty?
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ALL boys
very young girls everyone with abnormal GnRH stimulation test |
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What is a positive GnRH stimulation test?
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above 5IU/L of LH
rise in LH is usually positive no rise is negative |
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What are causes of peripheral precocious puberty in boys?
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Adrenal tumors, leydig tumors
B-hcg tumors, nonclassic CAH |
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What are cause of peripheral precocious puberty in girls?
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Adrenal tumors, virilizing ovarian tumors, nonclassic CAH, McCune-Albright syndrome
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What does McCune-Albright syndrome look like?
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In girls, cafe au lait spots
polyostotic fibrous dysplasia precocicous puberty hyperthyroidism |
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What is premature thelarche?
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Very common
Palable breast tissue in first 2 years No pubes |
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A 6 year old girl has pubes but no breast development what do they have and how do you treat?
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Premature adrenarche
No tx |
