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46 Cards in this Set

  • Front
  • Back
Determine lipoprotein levels–obtain complete lipoprotein profile after?
after a 9- to 12-hour fast.
LDL Cholesterol



Optimal




Primary Target of Therapy




<100


LDL Cholesterol




Near optimal/above optimal




Primary Target of Therapy

100-129

LDL Cholesterol




BODERLINE HIGH




Primary Target of Therapy

130-159

LDL Cholesterol



HIGH



Primary Target of Therapy

160-189
LDL Cholesterol



VERY HIGH





Primary Target of Therapy

>190
DESIRABLE

Total Cholesterol

<200

Total Cholesterol


BODERLINE HIGH

200-239

Total Cholesterol


HIGH

>240
LOW HDL Cholesterol
<40

HIGH HDL Cholesterol

>60
Major Risk Factors (Exclusive of LDL Cholesterol) That Modify LDL Goals
DM

Cigarette smoking


Hypertension (BP >140/90 mmHg or on antihypertensive medication)


Low HDL cholesterol (<40 mg/dL)


*Family history of premature CHD (CHD in male first degree relative <55 years;CHD in female first degree relative <65 years)


Age (men >45 years; women >55 years)


* HDL cholesterol >60 mg/dL counts as a “negative” risk factor; its presence removes onerisk factor from the total count.

TRIGLYCERIDES


normal

<150

TRIGLYCERIDES

Borderline high

150-199

TRIGLYCERIDES

High

200-499
TRIGLYCERIDES

Very High

> or= 500

Which pts do you treat aggressively for hyperlipidemia?

Pts with


1 DM


2 CAD


3 Stroke

Other name for Gemfibrozil

Lopid


Alcohol Avoid- Very serious interactions can Drug class: Fibric acid






Shouldn't be used if Serum creatinine >2 mg/dl

M3 for Vit D if?

If kidney dysfunction, call nephrologist can't be activated Consult Nephrologist

Metformin


Class?


Other name(s)?


Containdicated if creatinine is?

Class: Biguanide


Other names: Glumetza, Riomet, Glucophage, and Fortamet


Creatinie should be >1.5 mg/dl (male); 1.4 mg/dl (women)

Lovenox should be dose adjusted if eGFR?

eGFR<30


or they can be changed to Heparin

NYHA Class 1
No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea (shortness of breath).
NYHA Class 2
Slight limitation of physical activity. Comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea (shortness of breath).

NYHA Class 3

Marked limitation of physical activity. Comfortable at rest. Less than ordinary activity causes fatigue, palpitation, or dyspnea.

NYHA Class 4

Unable to carry on any physical activity without discomfort. Symptoms of heart failure at rest. If any physical activity is undertaken, discomfort increases.

ACC/AHA Stage A

Predisposing factors but no structural heart dx






Equiv NYHA Class: None

ACC/AHA Stage B

Structural heart dx but no symptoms




Equiv NYHA Class: 1

ACC/AHA Stage C

Structural heart dx with HF symptoms that are not present at rest






Equiv NYHA Class: 2 or 3

ACC/AHA Stage D

Symptoms at rest that are refractory to medical tx






Equiv NYHA Class: 4

Identify presence of clinical atherosclerotic disease that confers high riskfor coronary heart disease (CHD) events (CHD risk equivalent)?
CHD risk equivalents

■ Clinical CHD


■ Symptomatic CAD


■ PAD


■ AAA

Nitrofurantoin


Other name?


Don't use if?

Macrobid


Don't use if serum creatinine's elevated or eGFR<60 risk of neurotoxicity

Biphosphonates should be avoided if

eGFR<35


Select M5 alt med


Can be contraindicated if pt has CKD

If pt has hypertriglyceridemia pt should not take Lovastatin

Lovastatin is not active on triglycerides




M5 alt med Lovastatin does not reduce triglycerides




Brands: Mevacor and Altoprev

Normal eGFR

Because the calculation works best for estimating reduced kidney function, the National Kidney Foundation (NKF) suggests only reporting actual results once values are < 60 mL/min (they state normal values as 90-120 mL/min).



An eGFR below 60 mL/min suggests that some kidney damage has occurred.

Other name for atorvastatin
Brands: Lipitor

Other name for (ezetimibe/simvastatin)

vytorin

Other name for simvastatin

Zocor

Ezetimibe
Zetia or Ezetrol



is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the smallintestine. It may be used alone when other cholesterol-lowering medications are not tolerated, or together with statins - Vytorin

With liver dx, avoid these meds?

1 Acetaminophen


2 Alfusozin (Uroxatral)


3 Statins


4 Niacin (Niaspan)


5 Fibrates (active liver dx)


6 Oral Contraceptives


7 Oxycontin


8 BRILINTA® (ticagrelor)‎




Select M5 Alt med recommended (list med) contraindicated for members with liver dx

Other name for (ticagrelor)‎


BRILINTA®



Blood thinner that can prevent stroke, heart attack, and other heart problems.

Avoid which meds with PUD, GERD

1 NSAIDS


2 Celebrex


3 Potassium oral ER


4 ASA


5 Antiplatelets


6 Warfarin


7 Niacin (Niaspan)

Geodan


other name


don't use w/ pt's who've had an MI

Ziprasidone


can prolong the QTI


increased risk for torsades

Avoid which meds with MI

1 Oral Contraceptives


2 5 HT1 agonists


3 TCAs Amitriptyline

Triptans 5HT1 Receptor Agonist
Triptans 5HT1 Receptor Agonist

Sumatriptan (Imitrex)


Rizatriptan (Maxalt)


Zolmitriptan (Zomig)


Eletriptan (Relpax)


Naratriptan (Amerge)




don't cause vasospasms of the coronary arteries


Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches

TCAs Amitriptyline contraindicated with CAD

AND MI b/c?

can increase risk of arrythmias

PDE-5 Inhibitor

Phosphodiesterase inhibitor

Sildenafil (Viagra)

Tadalafil (Cialis)


Vardenafil (Levitra)


Avanafil






The phosphodiesterase type 5 (PDE5) inhibitors cause vasodilation in the penis and lung by blocking the breakdown of cyclic guanosine monophosphate (cGMP) which results in prolongation of the action of mediators of vasodilation including nitric oxide (NO)