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19 Cards in this Set

  • Front
  • Back
arterial pH
7.4
intracellular ph
7
venous pH
7.36
Where does acid in our body come from?
oxygen metabolism
What acids are produced by metabolism?
-CO2
-Lactate
-Pyruvate
-Ketoacids
How much acid do we eliminate daily via respiratory means?
12 M CO2 / day!
How much acid do we eliminate daily via renal mechanisms?
0.1 Mol
Why is it important that respiratory mechanisms eliminate more?
Because they can respond VERY RAPIDLY to changes in acid base status.
How long do the kidneys take to correct acid base abnormalities?
Days
Why do we use the anion gap in evaluating acid base abnormalities?
Because it shows when there are other nonroutinely measured acids present in the body.
What acids will cause a high anion gap?
-LACTATE
-KETOACIDS
-PHOSPHATE
How is the anion gap calculated?
Na + K - (Cl+Hco3)
What is an important intracellular buffering system?
Bicarb/CA in RBCs
What is base excess?
The amount of acid required to restore 1 liter of blood to its normal pH
Why isn't bicarb effective in evaluating acid/base status cases?
Because it is affected by both respiratory and metabolic abnormalities.
What does a BE < 0 mean?
Acidosis
What does a BE > 0 mean?
Alkalosis - there is excess base
What kind of disturbance is BE specific for?
Metabolic
What is the rule for determining if it's a respiratory acidosis or a metabolic alkalosis?
For ever 10 mm Hg increase in PCO2, the bicarb will increase by 1 mmol.