Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
arterial pH
|
7.4
|
|
|
intracellular ph
|
7
|
|
|
venous pH
|
7.36
|
|
|
Where does acid in our body come from?
|
oxygen metabolism
|
|
|
What acids are produced by metabolism?
|
-CO2
-Lactate -Pyruvate -Ketoacids |
|
|
How much acid do we eliminate daily via respiratory means?
|
12 M CO2 / day!
|
|
|
How much acid do we eliminate daily via renal mechanisms?
|
0.1 Mol
|
|
|
Why is it important that respiratory mechanisms eliminate more?
|
Because they can respond VERY RAPIDLY to changes in acid base status.
|
|
|
How long do the kidneys take to correct acid base abnormalities?
|
Days
|
|
|
Why do we use the anion gap in evaluating acid base abnormalities?
|
Because it shows when there are other nonroutinely measured acids present in the body.
|
|
|
What acids will cause a high anion gap?
|
-LACTATE
-KETOACIDS -PHOSPHATE |
|
|
How is the anion gap calculated?
|
Na + K - (Cl+Hco3)
|
|
|
What is an important intracellular buffering system?
|
Bicarb/CA in RBCs
|
|
|
What is base excess?
|
The amount of acid required to restore 1 liter of blood to its normal pH
|
|
|
Why isn't bicarb effective in evaluating acid/base status cases?
|
Because it is affected by both respiratory and metabolic abnormalities.
|
|
|
What does a BE < 0 mean?
|
Acidosis
|
|
|
What does a BE > 0 mean?
|
Alkalosis - there is excess base
|
|
|
What kind of disturbance is BE specific for?
|
Metabolic
|
|
|
What is the rule for determining if it's a respiratory acidosis or a metabolic alkalosis?
|
For ever 10 mm Hg increase in PCO2, the bicarb will increase by 1 mmol.
|
