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14 Cards in this Set
- Front
- Back
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Why is it important to distinguish Mansonella from other filarial worms (2 reasons)
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- Can be confused with other filarial worms, but respond to treatment differently
- If co-infection with other worms, very careful treatement is needed to cure, killing all worms at once can trigger Mazotti reaction |
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List several symptoms of Mansonella
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-itch
-calabar sweling, swellings of eye-lids - severe liver pain |
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what is the vector of Mansonella perstans and M. strptocerca
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-midges
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what are the vectors of Mansonella ozzardi?
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midges
black flies |
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What are the aquatic stages of Mansonella perstans vector?
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Larvae
Pupae |
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Name 3 common features of 3 Mansonella species we have studied, which might help to distinguish them from other filarial worm
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-Unsheathed microfilaria
-very small microfilaria -adults are small -microfilaria is non-periodic |
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on the blood smear, what would be a characteristic feature of M. strptocerca microfilaria
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shape of the shepherd's crock
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Distinguish between preferable adult habitat in human for all three Mansonella species:
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M. Streptocerca---------------dermis
M. ozzardi-----visceral adipose M. perstans--------- peritoneal cavity or pleural cavity, occasionally pericardial cavity, occasionally pericardial cavity |
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Distinguish between geographic distribution of all three Mansonella species
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M. streptocerca----Africa
M. Ozzardi----S. America and Caribbean islands M. perstans------S. America and Africa |
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What anti-filarial drug which also is used to treat Onchoserciassis has no effect on M. perstans?
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Ivermectin
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What anti-filarial durg which is used to treat Lymphatic Filariasis and Loasiasis has little or no effect on M. ozzardi
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DEC
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What anti-filarial drugs are extremely efficient in treating M. streptocerca?
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DEC and Ivermectin
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What is Mazotti reaction on many dead worms
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severe immune reaction on many dead worms
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list several ways to diagnose Mansonella
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blood smear
traveling history skin snip PCR diagnostics |
