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16 Cards in this Set
- Front
- Back
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Different types of IBD
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Ulcerative Colitis
Crohn's Collagenous Colitis Microscopic Colitis |
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UC vs. Crohns
1. Cause 2. Epidemiology 3. Smoking effects 4. Involvement |
1. Neither cause known
2. both in Western society 3. Smoking dec risk in UC and inc in Crohn's 4. UC-colon only from rectum up Crohn's-any part of gut, any order |
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UC vs. Crohns
1. kicker Sx's |
UC- normal perianal area, no abd mass
Crohn'- perianal skin tags, abd. mass present |
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UC vs. Crohns
1. Endoscopy |
1. UC-Rectum involved, continuous inflammation
Crohn's Rectum spared, discontinuous infl. |
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UC vs. Crohns
1. Contrast X-Ray (barium) |
UC-continuous superficial ulceration, lead pipe in chronic
Crohn's- discontinuous deep, rose thorn ulcers |
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UC vs. Crohns
1. Histology |
UC - Diffuse, superficial infl., distorted crypts
Crohn's - Focal Infl, Transmural |
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UC vs. Crohns
1. strictures? 2. Fistulae? 3. Toxic Colon |
UC-Rare, Very Rare, Maybe
Crohn's- Common, Common, very rare |
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UC vs. Crohns
1. Perf 2. Cancer risk 3. Massive bleeding |
UC-uncommon, Very high, uncommon
Crohn's - uncommon, high, increased |
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UC Rx
1. left sided only |
INDUCTION OF REMISSION: Topical Steroids or Topical 5-amino salicylic acid (can go PO if no response)
MAINTENANCE: Topical 5-ASA |
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UC Rx
2. Mild Total Colitis |
2. INDUCTION: Sulfasalazine or 5-ASA +- steroids
MAINTENANCE: same w/o steroids |
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UC Rx
Moderate total colitis |
INDUCTION: same as above plus AZA or 6-MP
MAINTENANCE: same, but maybe not AZA/6-MP |
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UC Rx
Severe Total Colitis |
INDUCTION: IV Steroids, IV Cyclosporin/Infliximab, Steroids
MAINTENANCE: Maybe Infliximab |
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Crohn's Rx
Mild |
INDUCTION: PO 5-ASA or Steroids
MAINTENANCE: 5-ASA + AZA/6-MP |
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Crohn's Rx
Moderate |
INDUCTION: PO 5-ASA +/- Steroids
MAINTENANCE: 5-ASA + AZA/6-MP |
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Crohn's Rx
Severe |
INDUCTION: IV Steroids or Infliximab + antibiotics
MAINTENANCE: 5-ASA + AZA/6-MP or Infliximab |
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Locations and examples of Extraintestinal Complications of IBD
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SKIN/MUCOSA: Erythema Nodosum, Pyoderma Gangrenosum
EYE: conjuntivitis, uveitis BONE/JOINTS: Sacroileitis, Arthritis, Ankylosing Spondylitis LIVER/BILIARY: Fatty Liver, PSC, Gallstones, Cholangiocarcinoma |
