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14 Cards in this Set
- Front
- Back
Well-circumscribed Mass: Benign
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Cyst
Fibroadenoma (and variants) Lipoma Fibroadenolipoma (hamartoma) Phylloides tum (usu lobulated) Oil cyst Galactocoele Hematoma (can be ill-defined) Intramammary lymph node Papilloma Hemangioma Skin mole (nevus) Sebaceous cyst (usually dense and superficial, axilla most common) Accessory nipple Silicone granuloma or nodule (in patients with/post implants) Pseudotumor |
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Well-circumscribed Mass: Cancer
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Papillary CA
Intracystic CA (often papillary) Mucinous CA (usually fuzzy on mag views) [= colloid CA] Medullary CA NOS Ductal CA (even intraductal can be large, to 6 cm) Mets (from anywhere, includes sarcoma & lymphoma, latter are rare breast primaries) |
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Spiculated mass
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Breast CA (usu invasive; includes ductal +variants such as tubular, and invasive lobular)
Radial scar (sclerosing ductal hyperplasia = benign sclerosing lesion of breast; central elastosis; “black star”; assoc. with or marker for possible CA; EXCISE) Post-surgical scar Previous trauma/resolving hematoma Sclerosing adenosis Fibrocystic changes Granular cell myoblastoma (probably from Schwann cells) Desmoid |
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Axillary LAD: Bilateral
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Breast CA with contralat spread (rare unless CA is bilateral)
Lymphoma/CLL Mets (melanoma, lung, head and neck CA) Drug reaction (Dilantin, pseudolymphoma) Rheumatoid arthritis SLE Granulomatous disease Mixed Connective Tissue Dz AIDS |
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Axillary LAD: Unilateral
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Primary breast cancer with ipsilateral spread (primary may be occult; Tx for adeno presumptive, go to mastectomy)
Sinus histiocytosis (reactive to breast cancer in same breast) Infection (mastitis, or occasionally an upper extremity infection such as paronchyial) Primary breast cancer arising in node (rare) Any of above bilateral, seen only on one side Silicone LAD (leaky implants, include gel bleed) |
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Skin thickening
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Inflammatory CA
Post surgical Keloids Focal mastitis Thyroid acropachy Dermatomyositis Normal variant for medial and inferior skin to be >2 mm, <5mm Fungal infection |
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Types of Invasive Breast CA
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Ductal (80-90%)
Lobular (~10%, usu older [50s-60s], often missed, infiltration of cells, often no mass, never has microcalcs) Medullary (<5%, lobulated, most are not pure, actually no sign difference in prognosis, usu younger pts[40s]) Tubular (2%, very well-diff, mc spiculated small mass, prognosis excellent <1 cm) Papillary (1-2%, very good prognosis even when large) Mucinous (Good prognosis, rare cells in PAS+ mucin) Minor rare variants |
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Types of DCIS
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COMEDO (=high nuclear grade; dangerous; linear branching calcs; calcs map the cancer reasonably well); ? Does LUMP/RT work?
Low nuclear grade: papillary, micropapillary, cribriform, solid (calcs do not map the cancer well; look for multiple clusters for multifocality [= cancer in same quadrant at multiple sites]) |
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Benign appearing microcalcifications
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Skin (you have to think of them; clusters/rosettes, classic ones have lucent centers; sites in axillary regions and cleavage; skin study with low exposure tangential view)
Milk of calcium in microcysts (need 90 degree and CC views = smiles vs smudges) Lobular calcifications (round) |
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Linear Calcifications
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Comedo type DCIS or intraductal extension from invasive primary
Secretory Dz (=benign ductal dz, plasma cell mastitis; can be tubular periductal calcifications or intraductal; classically bilateral and behind nipples) Single wall arterial calcification Suture calcifications (most often seen post RT) Milk of calcium (look for concavity superiorly) Fat necrosis (dangerous to call if not peripheral around a central lucency) |
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Increased Breast Densities
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Estrogen replacement (usually global, can be patchy, maybe 15% of patients on ERT have some effect, including cysts, soreness)
Weight loss (homogeneous putty look) Change in mammo technique (e.g., higher contrast processing, undercompression/under-exposure) |
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2 major categories of mammo findings that are interpreted as probably benign with recommendation for periodic surveillance:
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Localized findings: focal distribution and are found in one segment of one breast
Multiple similar lesions (usually three or more lesions, either tiny calcifications or circumscribed masses), randomly distributed in both breasts |
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WORK-UP FOR AND PERIODIC SURVEILLANCE OF PROBABLY BENIGN LESIONS
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US is performed for the nonpalpable, apparently circumscribed, noncalcified mass to establish or exclude a diagnosis of simple cyst
Solid masses, focal asymmetric densities, and lesions involving microcalcifications necessitate spot compression magnification mammography to clearly portray the shapes and marginal characteristics of the lesions and also to serve as a fine-detail source for comparison when additional fine-detail images are obtained later, during mammographic surveillance |
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Things to follow 6 months:
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Masses that are 75% well circumscribed, oval or round, without calcifications, non-palpable, not new, without worrisome findings or strictly benign findings (ie. cyst on u/s) on spot mags or ultrasound
Asymmetric densities (seen on two views and though to represent breast tissue) Clusters of rounded or oval calcifications similar in size or density (specifically not malignant looking) |