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14 Cards in this Set

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  • Back
What does ureteritis cystica predispose some to?
Ureteritis cystica is a manifestation of chronic inflammation. Predispose to bladder adenocarcinoma.
What is the most common complication of retroperitoneal fibrosis?
Hydronephrosis is the most common complication. May also cause right scrotal varicocele (obstruction of the right spermatic vein into the vena cava).
What failed in development that leads to exstrophy of the bladder?
Failure of the anterior abdominal wall and bladder. Bladder is exposed to the body surface. Associated with epispadias. RF for adenocarcinoma of the bladder.
Urachal cyst is a remnant of what?
Allantois. Urachus/allantois drains nitrogenous waste from fetus to mother in utero.
1. What are the RF for acute cystitis?

2. What causes (pathogens) acute cystitis?
1. Female, indwelling catheter (most common cause of sepsis in hospital), sexual intercourse, DM, neurogenic bladder, cyclophosphamide, Schistosoma hematobium.

2. E. coli (85%), Adenovirus (hem. cystitis), Staph. saprophyticus (young sexually active women), Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, N. gonorrhea.
Women presents with dysuria, increased frequency, urgency, suprapubic discomfort, and gross hematuria. Diagnosis? Whats the gold standard for diagnosing?
LUT infections (bladder, urethra). > 10^5 colony-forming units.
What is sterile pyruria?
Neutrophils in the urine and negative standard culture after 24 hours. Positive leukocyte esterase, negative nitrite. Causes: Chlamydia trachomatis, renal tuberculosis.
What causes Malacoplakia?
Chronic E. coli infection of the bladder. Yellow, raised mucosal plaques. Foamy macrophages.
1. What is the most common cause of bladder diverticula?
1. BPH.
Risk factors for TCC.
Smoking, workers in dye/rubber/leather, aniline, cyclophophamide, arsenic exposure, beer (nitrosamines), S. hematobium.
What country is SCC of the bladder abnormally high?
Where are the eggs of S. hematobium located in the bladder?
Egypt.
Urinary bladder venous plexus.
Whats the pathogenesis of the development of SCC due to S. hematobium?
Type II hypersensitivity. IgE attach to eggs, activate eosinophils, eosinophils release MBP which causes chronic bladder irritation - squamous metaplasia - dysplasia - SCC,
What are the risk factors for adenocarcinoma of the bladder?
Urachal remnants, cystitis glandularis, exstrophy of the bladder.
What is the most common sarcoma in children?
Embryonal rhabdomyosarcoma. Boys: urethra. Girls: vagina.