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60 Cards in this Set

  • Front
  • Back

Gametes (sex cells)

produced by each parent

Zygote (fertilized egg)

has combination of both parents’ genes

Our cells contain pairs of chromosomes

23

Crossing Over

Exchange of genetic material between non-sister chromatids of homologous chromosomes

Circumcision

Removal of the prepuce

Spermatic cord

bundle of fibrous connective tissue containing the ductus deferens, blood and lymphatic vessels, and testicular nerve

The human testes reside in the scrotum because

they need this cooler environment

Scrotum has three mechanisms to regulate temperature of the testes

Cremaster muscle:


Dartos muscle


Pampiniform plexus

Cremaster muscle

strips of the internal abdominal oblique muscle


In cold temperatures, contracts and draws testes upward toward body

Dartos muscle

subcutaneous layer of smooth muscle


Contracts when cold, wrinkling the scrotum, holding testes against warm body

Pampiniform plexus

: an extensive network of veins from the testes that surrounds the testicular artery and spermatic cord

Pampiniform plexus

Countercurrent heat exchanger—without the pampiniform plexus, warm arterial blood would heat the testis and inhibit sperm productionRemoves heat from the descending arterial bloodBy the time it reaches the testis, the blood is 1.5° to 2.5°C cooler

Testes (testicles

combined endocrine and exocrine glands that produce sex hormones and sperm

Seminiferous tubules

One to three in each lobuleEach tubule lined with a thick germinal epithelium for sperm generation

Interstitial (Leydig) cells between tubules produce

testosterone

Sustentacular cells in between germ cells

Protect the germ cells, and promote their development


Germ cells depend on them for nutrients, waste removal, growth factors, and other needs

Blood–testis barrier (BTB)—

formed by tight junctions between sustentacular cells


Separates sperm from immune system


Germ cells are immunologically different from body cells and would be attacked by the immune system

Spermatic ducts from testis

to the urethra

Efferent ductules

Transport sperm to epididymis

Duct of the epididymis (head, body, and tail

Site of sperm maturation and storage (fertile for 40 to 60 days)


Contains a single coiled duct, 6 m long, adhering to posterior of testis


Sperm mature as they travel through the duct


If not ejaculated, they disintegrate and epididymis reabsorbs them

Ductus (vas) deferens

Muscular tube, 45 cm (18 inches) long, passing up from scrotum through inguinal canal to posterior surface of bladder

Ejaculatory duct

2 cm duct formed from ductus deferens and seminal vesicle; passes through prostate to empty into urethra

Three sets of glands in male reproductive system

Seminal vesicles


Prostate gland


Bulbourethral (Cowper) glands

Seminal vesicles

Forms 60% of semen

Prostate gland

Thin milky secretion forms 30% of semen

Bulbourethral (Cowper) glands

Near bulb of penis


During sexual arousal, they produce a clear slippery fluid that lubricates the head of the penis


Protects the sperm by neutralizing the acidity of residual urine in the urethra

Benign prostatic hyperplasia (BPH

noncancerous enlargement of the prostate




Compresses urethra and obstructs flow of urine




Promotes bladder and kidney infections

Prostate cancer

Second most common cancer in men after lung cancer




Diagnosed from elevated levels of serine protease (PSA) and acid phosphatase in the blood

Reproductive system remains dormant for several years after birth

10 to 12 years in most boys; 8 to 10 years in most girls


Surge of pituitary gonadotropins awakens the reproductive system, leading to onset of puberty

As hypothalamus matures it produces

gonadotropin-releasing hormone (GnRH

GnRH stimulates anterior pituitary cells to secrete

Follicle-stimulating hormone (FSH)


Luteinizing hormone (LH)

Follicle-stimulating hormone (FSH)

Stimulates sustentacular cells which stimulates spermatogenesis

Luteinizing hormone (LH)

Stimulates interstitial cells to produce testosterone

Decline in testosterone secretion

Peak secretion at 7 mg/day at age 20


Declines to one-fifth of that by age 80


Decline in the number and activity of interstitial cells (testosterone) and sustentacular cells (inhibin)

Rise in FSH and LH secretion after age 50 produces male climacteric (andropause)

Most have little or no effect Some experience mood changes, hot flashes, “illusions of suffocation”

Erectile dysfunction (impotence)—

the inability to produce or maintain an erection sufficient for intercourse

Spermatogenesis

}processof sperm production in seminiferous tubules

Two forms of cell division

Mitosis


Meiosis

Mitosis

a body cell doubles its DNA and then divides to produce two genetically identical daughter cells Basis for division of the single-cell fertilized egg, growth of an embryo, all postnatal growth, and tissue repair

Meiosis

produces four gametes (haploid cells), each with only half the DNA of the diploid body cells

Once the primary spermatocyte undergoes meiosis, it

becomes genetically different and needs to be protected from the immune system

Spermiogenesis—changes that transform spermatids into

spermatozoa

Spermatozoon have two parts

head and tail

Spermatozoon


Head

contains the nucleus, acrosome, and basal body of the tail flagella

Spermatozoon


Nucleus

contains haploid set of chromosomes

Spermatozoon


Acrosome

enzyme cap over the apical half of the nucleus that contains enzymes that penetrate the egg

Two requirements for sperm motility:

elevated pH and an energy source

Chlamydia:

may cause urethral discharge and testicular pain

Bacterial STDs

Chlamydia


Gonorrhea


Syphilis

Gonorrhea

pain and pus discharge; may result in sterility from pelvic inflammatory disease

Syphilis:

hard lesions (chancres) at site of infection


Disappearance of chancres ends first stageSecond stage is widespread pink rashNeurosyphilis is third stage with cardiovascular damage and brain lesions

Viral STDs

Genital herpes

Genital herpes

most common STD in United StatesBlisters and pain

Genital warts

warts on perineal region, cervix, anusHepatitis B and C: inflammatory liver disease

Syphilis


Bacterial infection transmitted sexually or contracted congenitallyInfected fetuses are stillborn or die shortly after birth

Infection is asymptomatic for 2–3 weeksA painless chancre appears at the site of infection and disappears in a few weeks

Syphilis


If untreated, secondary signs appear several weeks later for 3–12 weeks, and then disappear: pink skin rash, fever, and joint pain

The latent period may or may not progress to tertiary syphilis, characterized by gummas (lesions (soft granulomas) of the CNS, blood vessels, bones, and skin)


Treatment: penicillin

HIV

50%The risk gay men in America face for contracting HIV.Overall for Americans, the risk is 1%.

Chlamydia


Most common bacterial STD in the United StatesResponsible for 25–50% of all diagnosed cases of pelvic inflammatory disease

Symptoms: urethritis; penile and vaginal discharges; abdominal, rectal, or testicular pain; painful intercourse; irregular menses


Can cause arthritis and urinary tract infections in men, and sterility in women


Treatment: tetracycline

Genital warts


Caused by human papillomavirus (HPV)

Second most common STD in the United StatesIncrease the risk of cancers in infected body regions

Genital herpes




Caused by human herpes virus type 2

Characterized by latent periods and flare-upsCongenital herpes can cause malformations of a fetus


Treatment: acyclovir and other antiviral drugs