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17 Cards in this Set
- Front
- Back
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Seminoma
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- Malignant
- Painless -affects ages 15-35 - Fried egg appearance - Radiosensitive - Most common Testicular germ cell tumor |
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Embryonal Carcinoma
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- Malignant Painful
- Worse prognosis - AFP and hCG markers |
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Yolk Sac tumor
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- Yellow mucinous
- Analgous to ovarian yolk sac tumor - Schiller-Duval bodies - Resembles primitive glomeruli - Increased AFP |
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Choriocarcinoma
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- Malignant
- hCG - Disordered syncytiotrophoblastic and cytotrophoblastic elements - Hematogenous metastases |
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Testicular non-germ cell tumors
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- Leydig cell
- Sertoli Cell - Testicular lymphoma |
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Peyronies disease
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- fibrosis of the penis causing curvature
- WNT pathway defect - Associated with Plantar Fibromatosis |
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Balanoposthitis
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- Inflammation of both the penis and the glans
- Sexually transmitted - Non-sexual (pyogenes, Fungus, Mycoplasm, Gardnerella) - Balanitis xerotic obliterans - Sclerosis of prepuce - Similar to Lichen sclerosis of the female genitalia |
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Bowen Disease
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- Men > 35
- Solitary Flat plaque squamous cell carcinoma in situ - May progress to SCC |
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Morphology of Testicular Atrophy
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- Prominent leydig cell sparing (Testosterone producing)
- Sertoli cell initally spared - |
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Causes of Testicular Atrophy
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- Atherosclerosis
- Cryptorchidism - Hypopituitarism - Malnutrition and cachexia - Hormone treatments - Klinefelter disease (primary) |
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Microscopic morphology of Mumps orchitis
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- Patchy interstitial infiltrates of mononuclear cells and late focal atrophy
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2 type of scrotal neoplastic masses
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- Lipoma
- Not a true neoplasm - Adenomatoid tumor - Most comon of the epididymis - Small descrete round nodule of gray tissue - Arises from mesothelium |
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Yolk sac Tumor or Endodermal sinus tumor
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- AFP marker
- Yellow cyst - Most common through age 3 - Shiller-duval glomeruloid bodies |
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Leydig tumor of the testis
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- Precocious puberty
- Gynecomastia - Tesicular enlargement - Crystaloids of Reinke - Most are benign - Distinct brown color |
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Fibroadenoma
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- Most common benign breast tumor
- Composed of fibrous and glandular tissue - Arises from specialized intralobular stroma - Hormonally responsive (changes size with menses or pregnancy) - Calcifies post-menospausaly - Common in < 30 y/o |
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Phyllodes
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- Aka: cystosarcoma phyllodes
- intralobular stroma - common in 6th decade of life - Local recurrences are more aggressive |
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What factors increase risk for breast cancer
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- Female
- Age - Age of menarche - First pregnancy - First degree relative - BRCA - Race - Previous Atypical breast biopsies |
