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22 Cards in this Set

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1. What electrolyte does the low volume state have?
⬆total Na, ⬇serum Na (dilutional effect), ⬇Cl, ⬇K
2. What pH does the low volume state have?
Alkalotic (except diarrhea, Renal Tubular Acidosis RTA type II, and DKA) because Aldosterone dumps H+.
3. What pH do vomiters have?
Alkalotic bc you vomit out H+.
4. What pH does diarrhea have?
Acidosis bc stool has bicarb.
5. What disease when pulse ⬆>10 on standing?
Hypovolemic shock
6. What disease when pulse ⬇<5 on standing.
Autonomic dysfunction
7. What are the symptoms of low energy state?
- CNS: mental retardation
- CVS: heart failure, pericardial effusion
- MSK: weakness, SOB, vasodilation, impotence, urinary retention, constipation.
- Rapidly dividing cells
8. What are the most common SIGNS of the low energy state?
Dyspnea & Tachypnea.
9. What are the most common SYMPTOMS of the low energy state?
Weakness & SOB.
10. What are the most common infection of LES?
UTI (UA) and Respiratory (C-XR).
11. What is the MCC of death in the LES?
Heart failure
Explain all obstructive lung disease.
Obstructive = airway problem (bacterial)

- Big mucus filled lungs (⬆RV, ⬆Reid Index = ⬆Airway thickness/ Airway lumen)
- Trouble breathing out: FEV1/FVC <0.8
- ABG: ⬆pCO2 = ⬆RR, ⬇pH
- Die of bronchiecstatis
- Ex: COPD
- Tx: Manipulate rate on ventilator, ⬆RR, ⬆Respiratory time, ⬆O2 if needed (to prevent free radical damage)
12. Explain all restrictive lung disease
Restrictive = interstitial problem (non-infectious/bacterial)

- Small stiff lungs (⬇Vital Capacity)
- Trouble breathing in (FEV1/FVC>0.8)
- Arterial Blood Gas ABG: ⬇pO2: ⬆RR, ⬇pCO2, ⬆pH
- CXR: reticulo-nodular pattern, ground-glass appearance.
- Die of cor-pulmonale.
- Ex: MSK disease (breathing out is passive), drugs, autoimmune.
- Tx: Pressure support on ventilator, ⬆O2, ⬆RR, ⬆inspiratory time.
13. What symptoms does a "more likely to depolarize" state have?
- BRAIN: psychosis, seizure, jittering.
- MSK: spasm, tetany
- SM: diarrhea, then constipation
- CARDIAC: hypotension, bradycardia.
14. What symptoms does a "less likely to depolarize" state have?
- BRAIN: lethargy, mental status change, depression
- MSK: weakness, SOB.
- SM: diarrhea, then constipation.
- CARDIAC: hypotension, bradycardia.
15. What is the humoral immune response?
B-cells and PMN's patrol the blood looking for bacteria.
16. What is the cell-mediated immune response?
T-cells and Macrophages patrol the tissues looking for non-bacteria.
17. What are macrophages called in each area of the body?
Blood - Monocytes
Brain - Microglia
Lung - T1 pneumocyte
Liver - Kupffer cells
Spleen - RED cells
Lymph - Dendritic cells
Kidney - Mesangial cells
Payers Patch - M cells
Skin - Langerhans
Bone - Osteoclasts

CT:
- Histiocytes
- Giant cells
- Epitheloid cells
18. What is the CBC for every vasculitis?
⬇RBC
⬇Platelet

⬆WBC
⬆T-cell
⬆Macrophages
⬆Schistocytes
⬆ESR
19. What is the time course of the inflammatory response?
1hr - swelling
Day 1 - PMN's shows up
Day 3 - PMN's peaks
Day 4 - MP/T-cell shows up
Day 7 - MP/T-cell peaks, Fibroblasts arrives
Day 30 - Fibroblasts peak
Month 3-6 - Fibroblasts leave
20. What state does estrogen minic?
The neuromuscular disease state (estrogen is a muscle relaxant).
21. What does high GABA levels lead to?
Bradycardia, lethargy, constipation, impotence, and memory loss.