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7 Cards in this Set

  • Front
  • Back
Hepatitis B virus:
1. type of genome
2. 2 steps in viral genome replication
3. 3 routes of transmission
4. Predominant result of infection
1. DNA

2. DNA -- RNA (viral RNA polym) -- DNA (viral reverse transc)

3. blood, sexual, placental

4. resolution
Describe the "window period" found in hepatitis B infection
period of time where HBeAg & HBsAg are not detectable in blood, while virus is incubating.

can often detect anti-HBc ab
Serologic findings in pts w/ chronic active HBV infection
continual high levels of HBsAg, HBeAg, and anti-HBc ab months to years after exposure.
Serological finding in pts immunized against HBV
positive HBsAb in serum
2 HBV txs
RT inhibitors, nucleoside analogues:
1. lamivudine
2. hepsera
Hepatits D virus:
1. another name?
2. What is required for infection?
3. genome
1. delta ag

2. HBV, either coinfection or superinfection

3. RNA
Hepatitis C virus:
1. genome
2. 3 routes of transmission
3. predominant result following exposure
1. + RNA

2. blood, sex, IVDU

3. persistent infection (assx, failure, cirrhosis, HCC)