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17 Cards in this Set

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Chlamydia:
1. genome
2. type of organism
3. key feature from cell membrane
4. dependent on what from host?
1. both DNA & RNA

2. obligate intracell bacteria

3. no PTG

4. need ATP from cell
Review the life cycle of Chlamydia:
--which form is infectious?
--which form is replicating?
2 genuses of Chlamydiaceae and dz causing spp
Chlamydia: C. trachomatis

Chlamydophilia: C. psittaci, C. pneumoniae
Chlamydia:
1. 3 parts to pathogenesis
2. Immunity?
1. access through abrasions, significant cell damage, induce inflammatory response

2. not long lived
Trachoma:
1. micro cause
2. organ affected, type of path
3. serotypes causing this dz
1. Chlamydia trachomatis

2. eye, chronic follicular conjunctivitis leading to scarring & blindness

3. A, B, C (not found in US)
5 types of infections caused by Chlamydia trachomatis
--which serotype(s) responsible?
1. Trachoma (A-C)

2. Genital tract infection (D-K)

3. inclusion conjunctivitis (D-K)

4. neonatal pneumonia (D-K)

5. lymphogranuloma venereum (L)
Chlamydia genital tract infection:
1. serotypes responsible
2. transmission, incubation
3. sxs in men (3), women (3), infants (1)
1. D-K

2. sexually, 2-6wk incubation

3. (generally assympto in adults)
--men: urethritis, epidymitis, prostatitis
--women: cervicitis, salpingitis, PID (infertility)
--infants: pneumonia
Chlamydia inclusion conjunctivitis:
1. serotypes found
2. cause
3. contrast w/ trachoma
1. D-K

2. contact w/ infected vaginal secretions

3. trachoma is caused by different serotypes (A-C) & more chronic dz; inclusion conjunctivitis is more acute
Chlamydia lymphogranuloma venereum:
1. transmission
2. result
3. 2 parts to tx
1. sexual

2. suppurative multilocular inguinal lymph nodes (bubos) forming: fistulas, strictures, abscesses

3. tetracycline, erthryomycin
3 non-culture means of dx Chlamydia trachomatis
1. direct fluorescent Ab

2. lipopolysaccharide enzyme assay

3. DNA probe of rRNA (combined w/ gonococcal screen)
4 ways to tx Chlamydia trachomatis
--which one for pregnant women?
1. Tetracyclines
2. Quinolones
3. Azithromycin
4. Erythromycin (pregnant)
Chlamydia pneumoniae:
1. 3 common clinical presentations
2. diagnosis
3. transmission
1. pharyngitis, laryngitis, walking pneumonia

2. acute & convalescent serology

3. respiratory spread
Chlamydia psittaci:
1. transmission
2. dz resulting
1. zoonotic: inhale respiratory secretions or droppings of infected birds (all, especially parrots & parakeets)

2. severe lower respiratory tract infection: dry cough, B/L pneumonia, fever
Mycoplasma pneumoniae:
1. describe membrane
2. requirement for growth
3. pathogenesis
1. no cell wall, single triple layered sterol membrane

2. cholesterol for membrane

3. attaches to bronchial epithelium, inflammatory response (superAG)
Mycoplasma pneumoniae:
--sxs
--CXR finding
4 uncommon dzs caused by Mycoplasma (NOT pneumonia)
1. dermatologic

2. cardiac

3. arthritis

4. neurologic
売り出し
/(n) (bargain) sale/
[うりだし]