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11 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
1. Basic definition of achalasia
2. 3 general anomalies found in achalasia
1. failure of esophagus to relax

2. --increased LES tone
--aperistalsis
--decreased LES relaxation w/ swallowing
2 key pathologic changes in achalasia
1. increased esophageal dilation above LES

2. decreased myenteric ganglia
1. Condition that leads to esophageal varices
2. Clinical presentation of varices
1. portal HTN causes increased venous volume at portal/systemic anastomoses

2. assymptomatic until rupture (high mortality)
1. 2 common location of Malloy-Weiis tears
2. General cause of M-W tears
3. Name for severe form*
1. gastroesophageal jxn, gastric cardia

2. severe vomiting/retching

3. BoerHaave syndrome - a rupture from severe heaving
3. Been heaving
2 common causes of infectious esophagitis
fungal (Canida)
virus (CMV, HSV)
5 general causes of reflux esophagitis (GERD)
1. decreased LES tone

2. sliding hiatal hernia

3. slowed clearance of refluxed contents

4. decreases gastric emptying

5. decreased repair capacity
1. What is Barrett's esophagus?
2. What is a common cause?*
3. 2 criteria for Dx
4. Major risk factor for what?*
1. switch in distal esophagus from non-keratinized str sq to sim columnar

2. GERD

3. endoscopic salmon color (NL = white), histologic goblet cells

4. Adenocarcinoma
BARRett's: Becomes adenocarcinoma, results from reflux
2 types of hiatal hernia
1. sliding: stomach and esophagus push up through esophagus

2. rolling: only a segment of stomach pushes up
Contrast the common locations of squamous cell carcinoma & adenocarcinoma in the esophagus
squamous cell: upper 2/3

adenocarcinoma: lower 1/3
Describe how the incidences of squamous cell carcinoma and adenocarcinoma have changed in the US
squamous cell incidence decreased

adenocarcinoma incidence increased
List the ABCDEF risk factors of esophageal cancer
Alcohol/Achalasia
Barrett's esophagus
Cigarettes
Diverticuli
Esophagitis/Esophageal webs
Familial