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35 Cards in this Set

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The term "enteric" pertains to what?
Pertains to small intestine
T/F - Enterobacteriaceae are ubiquitous
True. They are ubiquitous
T/F - Enterobacteriaceae are necessary for development, but not physiology.
False. They are necessary for physiology and development
List the six enteric bacteria that are of clinical importance.
E. coli
Klebsiella
Proteus
Salmonella
Shigella
Yersinia
Eeek Pussy
Enterobacteriaceae:

- shape
- gram what
- how does it utilize oxygen
bacill

Gram Negative

Facultative
What are the 7 major virulence factors of enterobacteriaceae?
1. Endotoxin (LPS - lipid A)

2. Capsule

3. Antigenic phase variation

4. Sequestration of growth factors

5. Type III secretion system

6. Antimicrobial resistance

7. Resistance to serum killing
ACE STAR
What is K antigen associated with?

What is H antigen associated with?
Capsule

Flagella
Kapsule

Powered by proton (H+) motive pump
How many pathogenic strains of e.coli are there that cause gastroenteritis?
Five
Which strains of gastroenteritis-causing e.coli exist in the developed countries?
Enterotoxigenic E.coli (ETEC)

Enterohemorrhagic E. coli (EHEC)
Developed countries are

High Tech
Which strains of gastroenteritis-causing e.coli exist in the Large Intestine?
Enterohemorrhagic E. Coli (EHEC)

Enteroinvasive E. Coli (EIEC)
Huge Intestine
Which strains of gastroenteritis-causing e.coli cause Traveler's Diarrhea?
ETEC

EAEC
Traveler's Ailment
Which strains of gastroenteritis-causing e.coli cause Infant Diarrhea?
EPEC

EAEC

ETEC
Report this to the PTA
Which strains of gastroenteritis-causing e.coli exist in ALL AGE groups?
EHEC
Which strains of gastroenteritis-causing e.coli does NOT cause FEVER?
EHEC
What is the common symptoms of all e.coli based gastroenteritis?
Watery Diarrhea
EHEC:

- how does it transmit to humans?
Cattle manure into soil/water will contaminate FOOD
Which strains of gastroenteritis-causing e.coli can survive the deadly acid of our stomachs?
EHEC
Which strains of gastroenteritis-causing e.coli progresses to Hemolytic Uremic Syndrome (HUS)?
EHEC
H = H
Urinary Tract Infection:

- which enterobacteriaceae
- what allows them target urinary tract
- progression
Uropathogenic E. Coli (UPEC)

Adhesins specific for GU epithelial cells

Ascending infection:
(urethra contamination, ascends bladder, migrate to kidnesy)
Urinary Tract Infection symptoms:

- Upper UTI x1
- Lower UTI x2
Pyelonephritis

Cystitis (Bladder)
Urethritis
UTI vs PCU
Urinary Tract Infection treatment:

- Upper UTI (drug & course)
- Lower UTI (drug & course)
Long term Ab (10 d)

Short term Ab (3 d)

Cephalexin with increased fluids
Long time to UP the hill

Short time to reach LOWER hill

b/c of big SWEATY big HEAD
UTI's are more prevalent in what population group?
Bitches by up to 14 times
What is the role of Lactobacillis is disease?

What can affect it? x2
Makes lactic acid, thus lowering pH and inhibiting bad bacteria in pussy.

Estrogen deficiency or Ab leads to reduction of Lactobacillus
Which E. coli strain is responsible for causing Neonatal Meningitis?
Strains with K1 capsular antigen
Kiddie meningitis
K1 ddie memingitis
Besides e.coli, what other bacterium can cause neonatal meningitis?
GBS
What are the classic symptoms of Neonatal Meningitis?
Fever
HA
Neck stiffness (hard to detect)
Are the classic symptoms of Bacterial Meningitis primary to meningits?

If not, what is it primary to and what symptoms are more associated with meningitis?
No.

More primary to system illness (sepsis)

Decreased responsiveness is more associated with it.
How is the diagnosis of Neonatal Meningitis made?
Grow bacteria from CSF or blood
What are the general diseases caused by E. coli? x5
Gastroenteritis
UTI
Neonatal Meningitis

Bacteremia
Intraabdominal infection
E. Coli Bacteremia/Septicemia usually originates from what source?
Endogenous source

(e.g. - GI or urinary tract)
How does E. Coli become bacteremic from its original source?
Perforation
Translocation
Catheterization
Intraabdominal infections are associated with what physiological event?
Intestinal perforation
E.coli (in general) treatment?
Symptomatic treatment

using

Susceptibility tests for Ab therapy
What are some preventative E.coli methods? x2
High hygiene

Proper cooking
If a patient comes to you with diarrhea, what is the proper method to get diagnosis?
Get HISTORY

Then do lab work