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35 Cards in this Set
- Front
- Back
- 3rd side (hint)
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The term "enteric" pertains to what?
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Pertains to small intestine
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T/F - Enterobacteriaceae are ubiquitous
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True. They are ubiquitous
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T/F - Enterobacteriaceae are necessary for development, but not physiology.
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False. They are necessary for physiology and development
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List the six enteric bacteria that are of clinical importance.
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E. coli
Klebsiella Proteus Salmonella Shigella Yersinia |
Eeek Pussy
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Enterobacteriaceae:
- shape - gram what - how does it utilize oxygen |
bacill
Gram Negative Facultative |
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What are the 7 major virulence factors of enterobacteriaceae?
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1. Endotoxin (LPS - lipid A)
2. Capsule 3. Antigenic phase variation 4. Sequestration of growth factors 5. Type III secretion system 6. Antimicrobial resistance 7. Resistance to serum killing |
ACE STAR
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What is K antigen associated with?
What is H antigen associated with? |
Capsule
Flagella |
Kapsule
Powered by proton (H+) motive pump |
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How many pathogenic strains of e.coli are there that cause gastroenteritis?
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Five
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Which strains of gastroenteritis-causing e.coli exist in the developed countries?
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Enterotoxigenic E.coli (ETEC)
Enterohemorrhagic E. coli (EHEC) |
Developed countries are
High Tech |
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Which strains of gastroenteritis-causing e.coli exist in the Large Intestine?
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Enterohemorrhagic E. Coli (EHEC)
Enteroinvasive E. Coli (EIEC) |
Huge Intestine
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Which strains of gastroenteritis-causing e.coli cause Traveler's Diarrhea?
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ETEC
EAEC |
Traveler's Ailment
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Which strains of gastroenteritis-causing e.coli cause Infant Diarrhea?
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EPEC
EAEC ETEC |
Report this to the PTA
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Which strains of gastroenteritis-causing e.coli exist in ALL AGE groups?
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EHEC
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Which strains of gastroenteritis-causing e.coli does NOT cause FEVER?
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EHEC
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What is the common symptoms of all e.coli based gastroenteritis?
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Watery Diarrhea
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EHEC:
- how does it transmit to humans? |
Cattle manure into soil/water will contaminate FOOD
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Which strains of gastroenteritis-causing e.coli can survive the deadly acid of our stomachs?
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EHEC
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Which strains of gastroenteritis-causing e.coli progresses to Hemolytic Uremic Syndrome (HUS)?
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EHEC
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H = H
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Urinary Tract Infection:
- which enterobacteriaceae - what allows them target urinary tract - progression |
Uropathogenic E. Coli (UPEC)
Adhesins specific for GU epithelial cells Ascending infection: (urethra contamination, ascends bladder, migrate to kidnesy) |
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Urinary Tract Infection symptoms:
- Upper UTI x1 - Lower UTI x2 |
Pyelonephritis
Cystitis (Bladder) Urethritis |
UTI vs PCU
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Urinary Tract Infection treatment:
- Upper UTI (drug & course) - Lower UTI (drug & course) |
Long term Ab (10 d)
Short term Ab (3 d) Cephalexin with increased fluids |
Long time to UP the hill
Short time to reach LOWER hill b/c of big SWEATY big HEAD |
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UTI's are more prevalent in what population group?
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Bitches by up to 14 times
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What is the role of Lactobacillis is disease?
What can affect it? x2 |
Makes lactic acid, thus lowering pH and inhibiting bad bacteria in pussy.
Estrogen deficiency or Ab leads to reduction of Lactobacillus |
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Which E. coli strain is responsible for causing Neonatal Meningitis?
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Strains with K1 capsular antigen
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Kiddie meningitis
K1 ddie memingitis |
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Besides e.coli, what other bacterium can cause neonatal meningitis?
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GBS
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What are the classic symptoms of Neonatal Meningitis?
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Fever
HA Neck stiffness (hard to detect) |
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Are the classic symptoms of Bacterial Meningitis primary to meningits?
If not, what is it primary to and what symptoms are more associated with meningitis? |
No.
More primary to system illness (sepsis) Decreased responsiveness is more associated with it. |
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How is the diagnosis of Neonatal Meningitis made?
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Grow bacteria from CSF or blood
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What are the general diseases caused by E. coli? x5
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Gastroenteritis
UTI Neonatal Meningitis Bacteremia Intraabdominal infection |
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E. Coli Bacteremia/Septicemia usually originates from what source?
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Endogenous source
(e.g. - GI or urinary tract) |
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How does E. Coli become bacteremic from its original source?
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Perforation
Translocation Catheterization |
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Intraabdominal infections are associated with what physiological event?
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Intestinal perforation
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E.coli (in general) treatment?
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Symptomatic treatment
using Susceptibility tests for Ab therapy |
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What are some preventative E.coli methods? x2
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High hygiene
Proper cooking |
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If a patient comes to you with diarrhea, what is the proper method to get diagnosis?
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Get HISTORY
Then do lab work |
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