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16 Cards in this Set
- Front
- Back
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What is the method of spread in most cases of osteomyelitis?
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Hematogenous - blood born
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What is the most commonly recovered organism causing osteomyelitis?
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Staphylococcus
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What particular organism is a frequent cause of osteomyelitis in patients with sickle cell disease?
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Salmonella
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What is the term given to describe a subperiosteal abscess which progresses, disrupts the blood supply and results in segmental bone necrosis in osteomyelitis?
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Sequestrum
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Osteomyelitis defined.
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Infection in the bone and/or marrow.
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What is Pott's disease?
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TB spondylitis
Vertebral involvement of TB Osteomyelitis |
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What are the common joints for RA?
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PIP,MCP, Wrists, Ankles, Fingers, Elbows
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What is spared by RA?
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DIP, T/L/S spine, and CMC
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What is RF?
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Antibody against the Fc protein of Ig. Usually IgM
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What are some cytokines involved in the destructive synovitis of RA?
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TNF-alpha
IL-1 |
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What virus has been proposed as an etiological agent of Paget's disease?
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Paramyxovirus
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What is the pathognomonic histologic appearance of bone in Paget's disease?
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Mosaic
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What are the 3 phases of Paget's disease?
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1. Osteolytic phase
2. Mixed Osteoblastic & osteolytic phase 3. Late phase |
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Describe the late phase of Paget's disease.
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Increased bone density,
thick trabecula, and prominent mosaic pattern |
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What is the most common clinical manifestation of Paget's disease?
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Arthritis due to rapid bone remodeling.
Erosion of articular surface leads to OA. |
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What are tumors associated with Paget's disease?
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Sarcoma
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