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84 Cards in this Set

  • Front
  • Back

adaptive immunity

the ability to recognize and remember specific antigens and mount an attack on them.

Humoral

B cells

cell-mediated immunity

t cells

adenoids

mass of lymphatic tissue in the nasopharynx

antibody

protein produced by B cells to destroy antigens

antigen

substance that the body recognizes as foreign; evokes an immune response. Most antigens are proteins or protein fragments found on the surface of bacteria, viruses, or organ transplant tissue cells

axillary nodes

lymph nodes in the armpit

B cell (B lymphocyte)

lymphocyte that matures into a plasma cell to secrete antibodies

cell-mediated immunity

T cells (cytotoxic helper and suppressor) respond to antigens and destroy them; a type of adaptive immunity

cervical nodes

lymph nodes in the neck region

complement system

set of proteins in the blood that help antibodies kill their target

cytokines

proteins secreted by cytotoxic T cells to aid in antigen destruction. Examples are interferons and interleukins



cytotoxic T cell

lymphocyte that directly kills antigens; called (CD8+) T cell



dendrite cell

antigen-presenting cell. Shows T and B cells what to attack

helper T cell

lymphocyte that aids B cells and stimulates T cells. Also called CD4+ T cell

humoral immunity

B cells produce antibodies after exposure to specific antigens; type of adaptive immunity

immunity

body's ability to resist foreign organisms and toxins that damage tissues and organs. This includes natural immunity and adaptive immunity

immunoglobulins

antibodies such as IgA, IgE, IgG, IgM and IgD secreted by plasma cells (mature B cells) in response to the presence of an antigen

immunotherapy

thee use of immune cells, antibodies, or vaccines to treat or prevent disease.

inguinal nodes

lymph nodes in the groin region

interferons

proteins (cytokines) secreted by T cells and other cells to aid and regulate the immune response

interleukins

proteins (cytokines) that stimulate the growth o f B and T lymphocytes

interstitial fluid

fluid in the spaces between cells. This fluid becomes lymph when it enters lymph capillaries

lymph

thin, watery fluid found within lymphatic vessels and collected from tissues throughout the body. Latin LYMPHA means clear spring water

lymph capillaries

tiniest lymphatic vessels

lymphoid organs

lymph nodes, spleen, and thymus gland

lymph node

collection of stationary solid lymphatic tissue along lymph vessels; contains cells (lymphocytes and macrophages) that fight infection

lymph vessel

carrier of lymph throughout the body; lymphatic vessels empty lymph into veins in the upper part of the chest

macrophage

large phagocyte found in the lymph nodes and other tissues of the body (Phag/o means to eat or swallow)

mediastinal nodes

lymph nodes in the area between the lungs in the thoracic cavity

mesenteric nodes

lymph nodes in the mesentery (intestinal region)

monoclonal antibody

antibody produced in a laboratory to attack antigens and to destroy cells; useful in immunotherapy

natural immunity

protection that an individual is born with to fight infection such as neutrophils, monocytes, macrophages and NK cells. It is not antigen specific and does not elicit memory

paraaortic nodes

lymph nodes near the aorta in the lumbar (waist) area of the body

plasma cell

lymphocyte that secretes antibodies. It matures from B lymphocytes

right lymphatic duct

lymphatic vessel in the chest that drains lymph from the upper right part of the body. It empties lymph into a large vein in the neck

spleen

organ in the left upper quadrant of the abdomen that destroys warn-out red blood cells, activates, lymphocytes and stores blood

suppressor T cell

lymphocyte that inhibits the activity of B and T cells. Also called a Treg (regulatory T cell)

T cell (T lymphocyte)

lymphocyte that acts directly on antigens to destroy them or produce chemicals such as interferons and interleukins that are toxic to antigens

tolerance

the ability of T lymphocytes to recognize and accept the body's own antigens as "self" or friendly. Once tolerance is established, the immune system will not react against the body

thoracic duct

large lymphatic vessel that drains lymph from the lower and left side of the body. It empties lymph into large veins in the neck

thymus gland

lymphoid organ in the mediastinum that conditions T cells to react to foreign cells and aids in the immune response

tonsils

masses of lymphatic tissue in the back of the oropharynx

toxin

poison; a protein produced by certain bacteria, animals, or plants

vaccination

exposure of an individual to a foreign protein (antigen) that provokes an immune response. the response will destroy any cell that possesses the antigen on its surface and will protect against infection. The term comes from the Latin VACCA, cow - the first inoculations were given with organisms that caused the disease cowpox to produce immunity to smallpox

vaccine

weakened or killed microorganisms, toxins, or other proteins given to induce immunity to infection or disease

immun/o

protection

lymph/o

lymph

lymphopoiesis

formation of lymphocytes or lymphoid tissue

lymphocytopenia

deficiency of lymphocytes in the blood. Often associated with susceptibility to infection

lymphocytosis

excess of lymph cells in the blood

lymphaden/o

lymph node

splen/o

spleen

splenomegaly

enlarged spleen

hypersplenism

a syndrome marked by splenomegaly and often associated with blood cell destruction, anemia, leukopenia and thrombocytopenia

thym/o

thymus glans

tox/o

poison, toxic

ana-

again, anew

anaphylaxis

unusual hypersensitivity to previously encountered foreign proteins or other antigens. Vasodilation and a decrease of blood pressure can be life-threatening

inter-

between.

-stitial

pertaining to standing or positioned

lymphoma

malignant tumor of lymph nodes and lymph tissue

lymphadenopathy

lymph nodes enlarge

hodgkin lymphona

identified by a type of malignant cell, the Reed-Sternberg cell

allergy

abnormal hypersensitivity acquired by exposure to an antigen

atopy

a hypersensitivity or allergic state arising from an inherited predisposition. A person who is atopic is prone to allergies

non- Hodgkin lymphoma

mostly B cell lymphomas and rarely T cell malignancies

multiple myeloma

malignant tumor of bone marrow cells. Composed of plasma cells

thymoma

malignant tumor of the thymus gland

CD4+ cell count

measures the number of helper T cells in the bloodstream of patients with AIDS

ELISA

screening test to detect anti-HIV antibodies in the bloodstream. for Ensyme Linked Immunosorbent Assay

immunoelectrophoresis

test that separates immunoglobuins

viral load test

measurement of the amount of AIDS virus (HIV) in the bloodstream

AIDS

acquired immunodeficiency syndrome

HAART

highly active antiretroviral therapy

HIV

human immunodeficiency virus - causes AIDS

HSV

herpes simplex virus

KS

Kaposi sarcoma

NHL

non-Hodgkin lymphoma

PI

protease inhibitor

RTI

reverse transcriptase inhibitor, for example zidovudine (Retrovir) or lamivudine (Epivir)

SCID

severe combined immunodeficiency disease

Treg

regulatory T cell (suppressor T cell)

Toxo

toxopasmosis - parasitic infection associated with AIDS