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63 Cards in this Set
- Front
- Back
What is the function of the lymphatic system?
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defends the body against environmental hazards and internal threats
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What are the primary cells ofo the lymphatic system?
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lymphocytes
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What do lymphocytes respond to?
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pathogens, abnormal body cells, foreign proteins
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What are lymphocytes surrounded by?
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lymph
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What does the lymph system include?
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lymphoid tissues and lymphoid organs scattered throughout the body
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What carries lymph from peripheral tissues to the venous system
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lymphatic vessels
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Where does the lymphatic network begin?
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lymphatic capillaries
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Where are lymph capillaries present?
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almost every tissue and organ in the body
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What are the four ways lymphatic capillaries differ from blood capillaries?
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1. originate as pockets rather than tubes
2. larger diameters 3. thinner walls 4. flattened or irregular outline |
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Is the basal lamina present in lymph capillaries?
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either absent or incomplete
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What does the region of overlap allow for with endothelial cells?
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acts as a one way valve and permits the entry of fluids and solutes
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Where does lymph flow from from the lymph capillaries to?
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larger lymph vessels
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Do lymphatic vessels contain valves?
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yes
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Are pressures high or low in the lymphatic vessels?
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low
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Where are lymphatic capillaries absent?
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areas that lack blood flow
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What are the two types of lymphatic vessels?
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deep and superficial
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Where are superficial lymphatics located?
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in the subcutaneous layer deep to the skin
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Where are the deep lymphatics located?
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near deep arteries and veins supplying skeletal muscles and other organs of th eneck, limbs, trunk, and walls of visceral organs
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What do lymphatic vessels converge to form?
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lymphatic trunks
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Where do lymphatic trunks empty into?
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thoracic duct and right lymphatic duct
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Where does the thoracic duct collect lymph from?
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-lower part of the body
-left side of head -left arm, left thorax |
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Where does lymph from the thoracic duct enter the blood?
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BETWEEN the left internal jugular vein and left subclavian vein
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Where does the right lymphatic duct collect blood from?
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-neck and head
-right side-arm, right thorax |
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Where does lymph from the right lymphatic duct enter the blood from?
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between the right internal jugular vein and the right subclavian vein
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What is the function of the cisterna chyli?
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recieves lymph from inerior part of the abdomen, pelvis, and lower limbsby the left lumbar trunks and intestinal trunk
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Where does the thoracic duct collect lymph from?
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bronchomediastinal trunk, left suclavian trunk, and left jugular trunk
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Where does the right lymphatic duct collect from?
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right jugular trunk, right subclavian trunk, right bronchmediastinal trunk
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What does the blockage of the lymphatic drainage called?
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lymphedema
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What is a closed end vessel system?
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dead end capillaries where everything goes into the lymph and doesnt come out
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What does interstitial fluid control?
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1. protein concentration
2. volume of interstital fluid 3. control pressure of IF |
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What does the closed end vessel system return?
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proteins and fluid to the blood
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What happens to high melecular weight proteins that cannot be absorbed from tissues?
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they are picked up from lymphatic tissue
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What is the concentration of protein in most tissues?
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2 g/dl
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What is the concentration of protein in the liver?
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up to 6 g/dl
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What is the concentration in the intestines?
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3-4 g/dl
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Where does lymphatic capillaries drain lymph from?
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interstitial spaces
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Lymphatic capillaries drain lymph from everywhere except what?
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superficial portions of the skin, CNS, muscle endomysium and bones
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What drains the areas that dont get drained from the lymphatic capillaries?
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sinuses that go to blood capillaries
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What are pre-lymphatics?
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minute interstitial channels that eventually flow into vessels
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What unites to form lymphatic vessels?
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lymph nodes
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Where do the subcutaneous tissue of skin unite to form?
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follow veins
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Where do the lymphatic vessels unite in the viscera?
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follow arteries to form plexuses
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What is the pathway the lymph follows to the heart?
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lymph capillaries-->vessels-->lymph nodes-->trunks-->ducts-->heart
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What are the five trunks?
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-lumbar
-intestinal -bronchomediastinal -subclavian -jugular |
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Where does the lumbar trunk drain from?
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the lower limbs, wall and viscera of pelvis, kidneys, adrenal glands, abdominal wall
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What does the intestinal trunk drain from?
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stomach, intestines, pancreas, spleen, part of liver
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What does the bronchomediastinal trunk drain from?
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thoracic wall, lung, heart
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Where does the subclavian trunk drain from?
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upper limbs
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Where does the jugular trunks drain from?
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head and neck
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What is the rate of lymph flow?
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120 mL/hr; 2-3 L/day
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What is the relationship between lymph flow and increased interstitial fluid pressure?
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any factor that increases interstitial fluid pressure increases lymph flow
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What are the four factors that increase lymph flow?
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1. decreased blood colloid osmotic pressure
2. increase in IF colloid osmotic pressure 3. increased capillary hydrostatic pressue (blood pressure) 4. increased permeability of capillaries |
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What effect does the lymphatic pump have on lymph flow?
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increases it
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What is the flow of interstitial fluid at rest?
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almost 0
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What is the relationship between lymphatic tissue and the efficiency of the pump
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the greater the pressure of lymph tissue, the greater the efficiency of the lymph pump
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What is intrinsic intermittent contraction?
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smooth muscle contraction segment by segment
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What happens whena vessel is stretched?
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smooth muscles contract
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What is external intermittent compression?
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any external factor that intermitently compresses the lymph vessel
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What are five things that could be exernal intermittent compression?
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-skeletal muscle contraction surrounding lymph vessels
-movement of body parts -breathing -pulsation of arteries adjacent to lymphatic vessels -compressing tissue outside of body |
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What are the two main factors that determine lymph flow?
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1. interstitial fluid pressure
2. activity of lymphatic pump |
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What are the two types of immunity?
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acquired and innate
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What is acquired or adaptive immunity?
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-specific
-contact with invader then produce antibodies against it |
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What is innate immunity?
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-nonspecific
-skin, mucous membranes, phagocytes, and chemicals in blood |