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38 Cards in this Set

  • Front
  • Back

What is respiratory diverticulum derived from

Outgrowth of proximal foregut of endoderm

What does respiratory diverticulum form

tracheal bud which grows into splanchnopleuric mesoderm

what happens to respiratory diverticulum in week 5

a septum grows, dividing trachea and oesophagus (tracheo-oesophageal septum).


tracheal bud then grows into splanchopleuric mesoderm.

what happens if tracheo-oesophageal septum fails to form

tracheoesophageal fistula forms, linking the two -> infection - failure to thrive

what does splanchnopleuric mesoderm form

- lining and glands of respiratory tract


- smooth muscle


- blood vessels


- cartilage


- visceral pleura

What is branching morphogenesis

each lung bud divides many times to form the bronchial tree

what are the 4 lung bud divisions

1 = primary bronchi formation


2 = secondary bronchi (lobar)


3 = segmental bronchi


4 = intra segmental (bronchopulmonary segments)

when do the 4 lung bud divisions occur

primary = 28 days


secondary = 33 days


segmental = week 7


intra-segmental =

when does respiratory epithelium appear

week 26, appears in the terminal bronchiole sacs - thins to simple squamous epithelium to allow gas exchange

when is surfactant produced

6 months - allow air spaces to inflate

surface markings of apex of lung

2-3cm above medial one third of the clavicle

surface markings of R lung

apex ->4th cc -> 6th cc - moves away from midline -> 8th cc midclavicular line -> 10th cc midaxillary line - 10th rib posteriorly is the base

surface markings of L lung

apex -> 4th cc - moves away from midline (cardiac notch) -> 6th cc -> 8thcc midclavicular line -> 10th midaxillary line - 10th rib posteriorly

surface markings of the oblique fissure

T3 to 6cc

surface marking of horizontal fissure

4cc to oblique fissure

surface markings of pleura

apex - 4thcc - 6cc - 8th rib midclavicular - 10th rib midaxillary - 12th rib posteriorly

where is costodiaphragmatic recess

v shaped recess in parietal pleura between thoracic wall and diaphragm - 5cm vertical between 8th and 10th rib on midaxillary line

what is function of costodiaphragmatic recess

for expansion during deep inspiration. fluids may collect here, pleural effusion.

4 parts to parietal pleura

1) cervical


2) diaphragmattic


3) mediastinal


4) costal

3 points of pleural reflection

1) sternal line - anteriorly


2) costal line - inferiorly


3) vertebral line - posteriorly

which nerves supply parietal pleura

diaphragmatic and mediastinal = phrenic nerve (C3, 4, 5)


costal = intercostal nerves

what holds the two pleural layers together

surface tension

tension pneumothorax

deviation of trachea AWAY from side of tension

where would you insert a chest drain

ideally 5th or 6th intercostal space midaxilla


or 2nd, 8th or 10th intercostal space if reasoning can be rationalised

structures in the hilum

bronchi


pulmonary arteries and veins


bronchial arteries and veins


bronchopulmonary lymph nodes


pulmonary plexus of nerves


pulmonary ligament

which nerve is anterior to hilum

phrenic nerve

which nerve is posterior to hilum

vagus nerve

Left Medial wall of the lung relations

aortic arch


descending aorta


pulmonary trunk


cardiac impression


left braciocephalic vein


oesophagus


subclavian artery

Right medial wall of the lung relations

arch of azygos vein


superior vena cava


inferior vena cava


right braciocephalic vein


oesophagus

which parts of the lung drain to right lymphatic duct

right lung and left lower lobe

which parts of the lung drain to thoracic duct

left lung upper lobe

what is the carina

cartilaginous ring within trachea at site of tracheal bifurcation

significance of carinal angle

indicates carcinoma of carinal lymph nodes

trachea anatomy

starts at C6 (cricoid cartilage)


bifurcates at T4 (sternal angle)


enters hilum at T5/6 (left primary bronchus passes under arch of aorta)

tracheal wall

incomplete C shapes of hyaline cartilage plus trachealis muscle. become complete cartilage rings at hilum.

function of trachealis muscle

contracts during coughing - reducing size of tracheal lumen to increase rate of airflow

tracheal nerve supply

autonomic = CN X and sympathetic