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12 Cards in this Set
- Front
- Back
Bronchiectasis definition
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permanent dilation of bronchi, w/ peri-bronchial inflam & organization w/ muco-purulent debris
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Bronchiectasis path
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- Impaired mucus flow -> microbial colonization -> microbial products (elastase)
– all of this causes mucus hypersecretion and structural damage |
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Bronchiectasis Sx
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cough, purulent sputum, hemoptysis, localized rales or rhonchi, and clubbing
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Bronchiectasis causes of impaired flow how?
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1) Obstruction to outflow
2) Abnormal mucus (CF) 3) abnormal ciliary function (1oCD) |
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Bronchiectasis treatment
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drainage, antibiotics, and bronchodilators – surgical resection is rarely needed
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Bronchiectasis radiology
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airway dilation which extends to the periphery
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Upper>lower lobe emphysema
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suggests centrilobular type, from smoking
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Lower>upper lobe emphysema
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suggests panlobular type, from A1AT deficiency
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BOOP definition
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Bronchiolar lumen and alveolar airspace fibroblastic proliferation
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BOOP clinical
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- acute onset cough, dyspnea, fever, and malaise
- multiple associations (collagen-vascular disease) - most patients respond to corticosteroids |
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BOOP radiology
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will show multiple patchy airspace infiltrates
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BOOP path
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will show patchy fibromyxoid plugs in distal bronchioles and alveoli, +/- endogenous lipid pneumonia
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