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10 Cards in this Set
- Front
- Back
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what causes 90% of lung cancers?
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smoking
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what does tobacco contain that causes metaplastic changes in the lungs?
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Pb-210 and Po-210
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how does radon cause lung cancer?
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it gets deposited into the lungs and decays into Pb-210 and Po-210 releasing alpha radiation right onto the lung tissue
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what are the biomarkers associated with lung cancer?
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- K-ras = poor outcome
- EGFR = overexpression promotes cancer growth - p53 = mutation result in loss of DNA repair - myc = cause DNA amplification/overexpression - microRNAs = interact with Kras, EGFR, p53 - Rb = a tumor suppressor that gets deleted |
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T or F: anytime you get a met it is automatically stage IV lung cancer.
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true
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what is a pancoast tumor?
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a tumor in the lung that is close to the brachial plexus. it impinges on the brachial plexus and causes pain and numbness in the arm
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what did the pallative care study show?
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that those patient who had less aggressive end of life care had a higher quality of life, less depression, and better survival
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what is the marker for asbestos exposure?
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benign pleural plaques
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how long of a latency period does mesothelioma have after exposure?
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20-40 years
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what is the gold standard for diagnosis of mesothelioma?
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thoracoscopic biospy
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