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45 Cards in this Set
- Front
- Back
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highest association with smoking
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sqaumous and epidermoid
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develops chronically in damaged airway and invades adj intrapulmonary lymphnodes
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squamous
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atelectasis, hemoptysis, post obstructive pneumonitis
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squam
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origninate in central portion of lung from major segmental bronchia
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sq
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early detection sputum
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sq
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met to regional lymphnodes
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sq
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central as perihilar mass usually with extensive lymphnode met
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small
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extrinsic compression=narrow bronchi
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small
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wide spread met common
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small
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agrressive to bone marrow liver brain
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small
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distinguished from others by its marked response to chemo
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small cell
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primary non smokerst
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adeno
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tumor on periphery--> hard to early detect
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adeno
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met early to nervous liver adrenal bone
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adeno
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can be associated with scar
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adeno
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acinar(largest) papillary solid with mucous formation, bronchioalveolar sub types
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adeno
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single peripheral nodule or coin lesion, multiple pulmonary nodules or as diffuse alveoar infiltrate which gorws along pre existing alveolar walls
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bronchoalveolar-adeno
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similar to adeno, met to GI
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large
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Diag of exclusion
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large
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symptoms from tumor
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hemoptysis, chest pain, cough dyspnea wheeze stridor wL
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extensive throax spread
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hoarseness, SVC syndrome, pleural or pericardial effusion, cardiac tamponade, dysphagia
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what may be first sign
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paraneoplastic syndromes
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systemic disorders
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anorexia fever malaise
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cutaneous disorders
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digital clubbing hypertrophic pulmonary osteoarthropathy
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rheum disorders
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polymyositis dermatoyositis
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ebdi dusirders
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cushing, hypercalcemia, inappropriate sec of ADH in small
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heme disorders
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anemia, leukocytosis, eosinophilia, thormbotic hemorrhagic dz
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lambert eaton
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small cell- subacute peripheral neuropathy, necrotizing myopathy binocular visual loss
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horners
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miosis, ptosis, enophthalmos, anhidrosis
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pancoast
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NV complaications of superior pulmonary ulcus tumoer involve cervical and first throacic nerves compressing brachial plexus, first and second ribs destroyed, shoulder arma nd arm pain along distribution of ulnar nerve
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Stage 1 non small cell
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lobectomy is satisfactory, in some cases a bi-lobectomy or pneumonectomy is required. surg resection
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stage 2 non small cell
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pneumonectomy for complete resection of tumor. 5 yr survival = 30% surg resection
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stage 3a non small cell
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• Surgical resection, particularly those with localized chest wall involvement and no lymph node metastasis
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stage IIIb and IV non small cell
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• Not surgical candidates
• Palliative radiation with cisplatin-based chemotherapy |
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intial drugs for non small cell
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cisplatin or carboplatin PLUS ONE:
• Pacitaxel • Docetaxel • Gemciabine • Vinorelbine • Irinotecan • Etoposide • Vinblastine • Monoclonal Antibody: target therapy metuximab, rituximab |
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treatment small cell extensive and limited
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both given chemo: Cisplatin and etoposide or Carboplatin and etoposide
Extensive stage Extensive: add • Cisplatin and irinotecan |
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neuroendocrine tumor
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carcinoid
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severity and range of neuroendocrine tumor depends on?
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size, produces hormones
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metastatic neuroendocrine
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weight loss, weakness, general malaise
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Octreotide scan
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carcinoid imaging
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iodine 131 meta iodobenzlguanidine
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carcinoid imaging
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least agressive
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carcinoid
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treatment carcinoid
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surgery
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sleeve resection in carcinoid
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section of airway containing tumor removed
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uses of endoscopic tumor ablation?
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treat bronchial obstruction or reduction of tumor prior to surg
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