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25 Cards in this Set

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What does the spinal cord do?
mediates simple reflexes

coordinated movements involving more than one muscle

receives info from descending tracts (pyramidal) from higher centers (cortex)

sends info (touch, pain) to higher centers in ascending tracts (medial lemniscus) to brain stem, cerebellum, cortex
Coordination of movement
information travels between segments to control many muscles
What is a syrinx
a huge cavity in the spinal cord extends all the way up to the brain

-can be caused by car crash
Autonomic Nervous System
Sympathetic Division
Parasympathetic Division
Sympathetic DIvision of Autonomic Nervous System
-preganglionic fivers are cholinergic and terminate on sympathetic ganglia adjeacent to spinal cord and other nearby ganglia
-postganglionic fibers terminate on organs and are mostly noradrenergic (use norepinephrine)

fight or flight
-prepare for energy expenditure
-increase heart rate and blood pressure
-sends blood to muscles
-decreases contraction of intestine
Parasympathetic Division of Autonomic Nervous System
ganglia tend to be located closer to the target organs, preganglionic cholinergic (like sympathetic div)

fibers terminating on organs are mostly cholinergic (use acetylcholine) or peptidergic (use nueropeptides)

prepare for energy conservation
-decreases heart rate and blood pressure
-sends blood throughout body (to gut)
-increases intestinal contraction
Medulla
inferior olivary nucleus

pyramid

medial lemniscus
Inferior Olivary Nucleus
receives inputs from brain and spinal cord, send outputs to cerebellum (climbing fibers)

part of medulla
Pyramid
fibers of pyramidal tracts from cortex to spinal cord

in medulla
Medial Lemniscus
principal ascending pathway from spinal cord for touch and pain

in medulla
Pons
directly bellow cerebellum

descending and ascending tracts to cerebellum from spinal cord and to the spinal cord from cerebellum

contains pontine nuclei and pontine tracts that assist in and coordinate massive flow of info from cortex to cerebellum (control of movement)
Midbrain examples
superior colliculus

periqueductal gray

substantia nigra

cerebral peduncle
superior colliculus
processes visual and auditory info for control of eye movements

midbrain
periqueductal gray
control of pain

stimulation causes inhibition of pain so great that major surgery can be performed without an anaesthetic
-can also reduce intractable pain

midbrain
substantia nigra
control of movement

many neurons of this nucleus contain dopamine
-use as synaptic transmitter


malfunction causes Parkinson's

midbrain
Cerebral Peduncle
contains major descending tracts from cerebellum to spinal cord (control of movement)

midbrain
What does the reticular formation do?
major role: control levels of arousal and attention

ascending projections are very wide
-spread and reach many areas of the brain including cortex

sustained input from reticular formation is essential for the maintenance of consciousness
-damage to these fibers can produce prolonged coma
Cerebellum Inputs
from mossy fibers: come directly from spinal cord, vestibular system, cortex, through pontine nuclei in pons

mossy fibers synapse onto granule cells that from parallel fivers

parallel fibers synapse onto purkinje cell dentrites

inputs also from climbing fibers from inferior olivary nucleus in medulla.
-synpase directly onto purkinje dendrites
What to mossy fibers synapse to?
granule cells that form parallel fibers
what do parallel fibers synapse to?
Purkinje Cell dendrites
Cerebellum Outputs
entire output provided by Purkinje cells

some axons go to vestibular nuclei and from there directly to spinal cord

most axons end in three clusters of cells = "deep cerebellular nuclei"

axons of these cells project to many parts of the brain that are involved in control of movement
Granule cell has close packings of unmyelinated axons. True or False?
True

these are the axons that synapse onto the purkinje cell dendrites
What does the cerebellum do?
planning movements together with cortex, particularly those that improve with practice

adjusting movements as they are made

control of posture

control of eye movements

motor learning, skilled movements and agility

cognitive functions (still poorly understood)
Basal Ganglia
principle basal ganglia are:
-cuadate nucleus
-putamen
-globus pallidus

closely linked to function to the substantia nigra in midbrain

function by modulating the flow of info to and from the cortex

particularly important for the control of movement
Diseases of Basal Ganglia
degenerate during aging

Huntington's disease:
-hereditary degeneration producing involuntary movements and loss of cognition

Parkinson's Disease:
-degeneration in substantia nigra and associated with basal ganglia
-causes tremor and lack of motor control