Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
28 Cards in this Set
- Front
- Back
|
what does a NBT test measure
|
mac and PMN production of H2O2 used in resp burst
|
|
|
negative NBT indicates what
|
chronic granulomatous disease
|
|
|
what is chronic granulomatous disease
|
inherited mutation in NADPH oxidase component
|
|
|
aspergillosis exist in what form both in nature and in the body
|
mycelium (mass of hyphae)
|
|
|
aspergillosis is (dimorphic/monomorphic)
|
monomorphic
|
|
|
normal innate defenses to aspergillosis infection
|
macs (1st line)
PMN DCs |
|
|
type of PAMPs present on fungi that help activate immune system
|
TLRs
|
|
|
role of antibody response in fungal infections
|
none
|
|
|
hyphae with <90 degree branching hyphae
|
aspergillus
|
|
|
3 clinical forms of aspergillosis
|
hypersensitivity
colonization (of mucous w/o invasion) invasive infection |
|
|
clinical signs of allergic bronchopulmonary aspergillosis
|
wheezing
fever rubbery brown mucous plug |
|
|
polymorphisms of what predispose to different aspergillosis infections
|
TLR
|
|
|
central bronchiectasis on CXR
|
allergic bronchopulmonary aspergillosis
|
|
|
what is aspergilloma
|
fungal masses that grow in preexisting lung cavities (fungus balls)
|
|
|
clinical signs of aspergilloma
|
hemoptysis
|
|
|
pt presents with hemoptysis
|
aspergilloma
|
|
|
crescent sign on xray or CT
|
aspergilloma
|
|
|
invasive tracheobronchial aspergillosis is almost exclusively found in this patient population
|
immunocompromised
|
|
|
pt presents with cough, SOB, and local tissue destruction
|
chronic pulmonary aspergillosis
|
|
|
risk factors for invasive aspergillosis
|
myelosuppression
neutropenia |
|
|
nonproductive cough
high fever pleuritic chest pain |
invasive aspergillosis
|
|
|
halo sign on CXR
|
invasive aspergillosis
|
|
|
clinical signs of pulmonary zygomycosis
|
hemoptysis
|
|
|
branches at 90 degrees
|
zygomycosis
|
|
|
condition assx with rhinocerebral zygomycosis
|
diabetic ketoacidosis
|
|
|
why is diabetic ketoacidosis favorable to rhinocerebral zygomycosis
|
high blood glucose and low tissue pH favors growth
|
|
|
two types of zygomycosis
|
rhinocerebral
pulmonary |
|
|
clinical signs of sick house syndrome
|
allergies
|
