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11 Cards in this Set

  • Front
  • Back

Metabolic control of blood flow

-Metabolites: Adenosine, Lactate, H+, K+


-Paracrine: Ang II , Histamine (dilation), Prostaglandins


-Other: decrease O2, increase CO2 (Dilation)

Myogenic control of blood flow

-Myogenic reflex: flow up, stretch up, SM constrict, flow down


-Nitric Oxide: Shear stress, Ca2+ up in cells, NO synthase activated, NO diffusion, Dilation

Autoregulation

-Ability of organ to maintain constant blood flow when arterial pressure changes


-Blood pressure in brain, kidney, and heart remain constant despite change in MAP


-Important in hemorrhage and hypertension

Hyperemia

-Increase blood flow to different tissues of the body (metabolic changes)


-Due to build up of wastes

Active hyperemia

-Increase in blood flow due to an increase in metabolism


-eg. -- blood flow to muscle during excersice

Reactive Hyperemia

-Short interruption of blood flow causes vasodilator and increased blood flow


-Lifting weights

Coronary blood flow


(Metabolic)

Active hyperemia: adenosine and hypoxia


Reactive Hyperemia: Compressed during contraction

Coronary blood flow


(Myogenic)

-Controlled by Nitric Oxide during shear stress

Left Ventricle coronary flow

Highest during diastole

Right ventricle coronary flow

-Arteries not occluded like left


-increase during systole because of driving pressure

Cerebral blood flow

Metabolic- Active hyperemia- hypercapnia (CO2 up)