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11 Cards in this Set
- Front
- Back
Metabolic control of blood flow |
-Metabolites: Adenosine, Lactate, H+, K+ -Paracrine: Ang II , Histamine (dilation), Prostaglandins -Other: decrease O2, increase CO2 (Dilation) |
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Myogenic control of blood flow |
-Myogenic reflex: flow up, stretch up, SM constrict, flow down -Nitric Oxide: Shear stress, Ca2+ up in cells, NO synthase activated, NO diffusion, Dilation |
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Autoregulation |
-Ability of organ to maintain constant blood flow when arterial pressure changes -Blood pressure in brain, kidney, and heart remain constant despite change in MAP -Important in hemorrhage and hypertension |
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Hyperemia |
-Increase blood flow to different tissues of the body (metabolic changes) -Due to build up of wastes |
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Active hyperemia |
-Increase in blood flow due to an increase in metabolism -eg. -- blood flow to muscle during excersice |
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Reactive Hyperemia |
-Short interruption of blood flow causes vasodilator and increased blood flow -Lifting weights |
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Coronary blood flow (Metabolic) |
Active hyperemia: adenosine and hypoxia Reactive Hyperemia: Compressed during contraction |
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Coronary blood flow (Myogenic) |
-Controlled by Nitric Oxide during shear stress |
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Left Ventricle coronary flow |
Highest during diastole |
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Right ventricle coronary flow |
-Arteries not occluded like left -increase during systole because of driving pressure |
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Cerebral blood flow |
Metabolic- Active hyperemia- hypercapnia (CO2 up) |