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24 Cards in this Set
- Front
- Back
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local A
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reversible conduction blockage of impulses w/o nerve damage
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Ester type
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procaine
tetracaine DO NOT CROSS PLACENTA metabolized in plasma & liver |
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Amide type
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lidocaine
bupivacaine ropivacaine metabolised in liver |
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MOA
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block Na+ conductance
Lido, bup, tetra - all incorpinto lipososomes for slower release H gate (inner gate is closed) |
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Placental transfer
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Plasma protein binding
Bupivacaine - 95% Lidocaine 70% |
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Clearance
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Epi - delays absorption and prolongs duration
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Side affects
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CNS - restless/tremors , depression of resp
CVS - after CNS depress heart, arteriolar dialation SMC - intest/bronch rlx, NO URTERINE contraction depression IV rxns |
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Topical blockers
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Tetracaine
Lidocaine Sphenopalatine ganglion block |
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LOCAL
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everything cept Tetracaine
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Open wounds
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inject directly, no anti-septic into wound
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PNS block
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Brach plex - supraclavicular approach
use all cept Tetracaine |
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Pudendal Nerve block
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go transvag approach
or transperinal |
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IV regional block (Bier's block)
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Lidocaine
Prilocaine remove blood from extermity..inject into vein |
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Lumbar epi N block
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Chloroprocaine (low pH)
everything else cept Lidocaine & procaine |
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Spinal block
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procaine
tetracaine lidocaine bupivcaine ropivacaine USE SAME VISCOSITY AS CSF so moves up and down the body |
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Lidocaine
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local
- antiarrythymic - rapid absorbed - needle free - trasdermal patch |
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Bupivacaine
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more SENSORY block then motor
- can be used for continuous anestheisa w/ indwelling cahethers - cardioTOX!! |
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articaine
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dental procedures..rapid
1-6 hrs |
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chloroprocaine
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for Back pain, rapid metabolism, short duration
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mepivacaine
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dont use in OB
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Prilocaine
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negligible vasodialation
- causes methemoglobneima |
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procaine
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metabolism form PABA...inhibits sulphoanmides
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tetracaine
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USED IN SPINAL
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ropivcaine
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long acting, epi and spinal
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