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7 Cards in this Set

  • Front
  • Back
What and how do locals work as a whole
Locals are non-reversible and theybind to voltage gated channels
What does NaV Stand for
When you see NaV it is the Na channel
How many stages of resting are there
There are 3 states resting
Test
test
What kind of effects can they have
Local can have systemic effects
Esters you need to know
Cocaine- comes as liquid and is typically used for ENT cases
Benzocaine- used as a spray for EGDs
Metabolized by plasma tissue cholinesterase by hydrolysis
Esters have the higher allergy potential
Tend to be shorter acting due to ready metabolism
Amides
Metabolized in the liver
Allergies is extremely rare

Longer acting due to being lipophilic